Is EGCG (Epigallocatechin Gallate) safe in cosmetics?
EGCG (Epigallocatechin Gallate) has a safety rating of "GOOD" in our database. EU status: permitted. US status: restricted. 1 toxicological study endpoint(s) are available in our database.
EGCG (Epigallocatechin Gallate)
Also known as: (-)-Epigallocatechin-3-o-gallate, (-)-Epigallocatechol gallate, Tea catechin, Teavigo, NVP-XAA 723 (+6 more)
INCI: EGCG
EGCG (Epigallocatechin Gallate) (CAS 989-51-5) is a cosmetic uv filter / sunscreen functioning as UV Filter. Reported NOAEL =50 mg/kg bw/day in Dog (ToxValDB_ECHA_IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 989-51-5 →
Auto-generated CPSR Part A draft with source citations
Regulatory Status
EU EU Status
permitted
US US Status
restricted
US Notes
Not approved as UV filter; regulatory status pending
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for EGCG (Epigallocatechin Gallate).
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for EGCG (Epigallocatechin Gallate). NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =50 mg/kg bw/day | oral | Dog | subchronic | ToxValDB_ECHA_IUCLID |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
Ceased manufacture
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Antioxidant
Expert Verdict
Expert safety assessment and concern-level summary for EGCG (Epigallocatechin Gallate).
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to EGCG (Epigallocatechin Gallate) by CAS number or substance name.
Studies
1
Lowest NOAEL
50 mg/kg bw/day
Highest NOAEL
50 mg/kg bw/day
ToxValDB_ECHA_IUCLID
Known Synonyms
(-)-Epigallocatechin-3-o-gallate
(-)-Epigallocatechol gallate
Tea catechin
Teavigo
NVP-XAA 723
L-Epigallocatechin gallate
Epigallocatechin-3-monogallate
UNII-BQM438CTEL
Epigallocatechin 3-gallate
[(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate
(-)-epigallocatechin 3-gallate
Chemical Function
Antioxidant
Regulatory Lists
Canada; pharmaceutical
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
EPIGALOCATECHIN GALLATE
ChEMBL ID
CHEMBL297453
Max Phase
3
Frequently Asked Questions
Is EGCG (Epigallocatechin Gallate) allowed in the EU?
EGCG (Epigallocatechin Gallate) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does EGCG (Epigallocatechin Gallate) do in cosmetics?
EGCG (Epigallocatechin Gallate) functions as: UV Filter. It is classified as a UV Filter / Sunscreen in our database. CAS number: 989-51-5.
What is the NOAEL for EGCG (Epigallocatechin Gallate)?
The NOAEL (No Observed Adverse Effect Level) for EGCG (Epigallocatechin Gallate) is =50 mg/kg bw/day based on a subchronic study via oral route in Dog. Source: ToxValDB_ECHA_IUCLID.
Is EGCG (Epigallocatechin Gallate) used outside cosmetics?
EGCG (Epigallocatechin Gallate) also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check EGCG (Epigallocatechin Gallate) compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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Good
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