Is Iodoform safe in cosmetics?
Iodoform has a safety rating of "POOR" in our database. EU status: prohibited. US status: restricted.
Poor
Cosmetic Ingredient
Iodoform
Also known as: EINECS 200-874-5, NCI-C04568, Trijodmethane, UNII-KXI2J76489
INCI: IODOFORM
Iodoform (CAS 75-47-8) is a cosmetic cosmetic ingredient functioning as Antimicrobial agent; functional fragrance. EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 75-47-8 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Iodoform is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H312, H319, H332, H336, H411, H315, H401).
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Antimicrobial agent; functional fragrance
Safety Rating
POOR
Chemistry & Identifiers
IUPAC Name
iodoform
InChIKey
OKJPEAGHQZHRQV-UHFFFAOYSA-N
Regulatory Status
EU EU Status
prohibited
US US Status
restricted
US Notes
Permitted — not specifically restricted under 21 CFR Parts 700–740. Subject to general safety requirement under FD&C Act §601
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Iodoform.
Calculate MoS for your specific formulation with the MoS Calculator.
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (1)
Carcinogen Classification
Iodoform | TR-110: Bioassay of Iodoform for Possible Carcinogenicity (CASRN 75-47-8) (1978 ) | 04/26/78 | No Evidence | No Evidence | No Evidence | No Evidence | Under the conditions of this bioassay, no convincing evidence was provided for the carcinogenicity of iodoform in Osborne-Mendel rats or B6C3F1 mice.
Source: NTP Technical Reports
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Biocide
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
FDA Indirect Food Contact Additives
Expert Verdict
Expert safety assessment and concern-level summary for Iodoform.
Regulatory Flags
fragrance-component
ifra_fragrance
Known Synonyms
EINECS 200-874-5
NCI-C04568
Trijodmethane
UNII-KXI2J76489
Chemical Function
Biocide
Fragrance
Regulatory Lists
Indirect additives food contact (10/2018)
Canada; pharmaceutical
Canada; pharmaceutical
active_ingredient; Europe; Pesticides
IFRA Transparency
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
IODOFORM
ChEMBL ID
CHEMBL1451116
Max Phase
3
Frequently Asked Questions
Is Iodoform allowed in the EU?
Iodoform EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Iodoform do in cosmetics?
Iodoform functions as: Antimicrobial agent; functional fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 75-47-8.
Is Iodoform used outside cosmetics?
Iodoform also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Iodoform have different safety status in cosmetics vs industrial chemicals?
Iodoform is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H312, H319, H332, H336, H411, H315, H401).
Compliance Tools
Check Iodoform compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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