Is Direct Red 81 safe in cosmetics?
Direct Red 81 has a safety rating of "POOR" in our database. EU status: prohibited. US status: prohibited.
Poor
Cosmetic Ingredient
Direct Red 81
Also known as: 2-Naphthalenesulfonic acid, 7-(benzoylamino)-4-hydroxy-3-[2-[4-[2-(4-sulfophenyl)diazenyl]phenyl]diazenyl]-, sodium salt (1:2), 2-Naphthalenesulfonic acid, 7-(benzoylamino)-4-hydroxy-3-((4-((4-sulfophenyl)azo)phenyl)azo)-, disodium salt, Disodium 7-benzamido-4-hydroxy-3-((4-((4-sulphonatophenyl)azo)phenyl)azo)naphthalene-2-sulphonat, Solaminrot 4B, Direct Red 81 disodium salt (+15 more)
INCI: DIRECT RED 81
Direct Red 81 (CAS 2610-11-9) is a cosmetic cosmetic ingredient functioning as Colorant. EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 2610-11-9 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Direct Red 81 is prohibited in EU cosmetics but has active industrial GHS classifications.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word
Chemistry & Identifiers
IUPAC Name
disodium;7-benzamido-4-hydroxy-3-[[4-[(4-sulfonatophenyl)diazenyl]phenyl]diazenyl]naphthalene-2-sulfonate
InChIKey
UFUQRRYHIHJMPB-UHFFFAOYSA-L
Regulatory Status
EU EU Status
prohibited
US US Status
prohibited
US Notes
Prohibited — not FDA-approved for cosmetic use
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Direct Red 81.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex II — Prohibited
Ref: 1267
(EC) 2009/1223
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (II - Prohibited)
ASEAN Cosmetic Directive (II)
Ref: 1267
BRIN Brazil/India Cosmetics
Brazil: Prohibited
India: Prohibited (GNRAS)
Additional Jurisdictional Restrictions (1)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| KR | prohibited | - | - |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Dye
Regulatory List Membership (2)
EU Banned in Cosmetics
EU CosIng Cosmetics Ingredient Database
Expert Verdict
Expert safety assessment and concern-level summary for Direct Red 81.
Regulatory Flags
colorant
eu_banned_cosmetics
eu_cosing_listed
Known Synonyms
2-Naphthalenesulfonic acid, 7-(benzoylamino)-4-hydroxy-3-[2-[4-[2-(4-sulfophenyl)diazenyl]phenyl]diazenyl]-, sodium salt (1:2)
2-Naphthalenesulfonic acid, 7-(benzoylamino)-4-hydroxy-3-((4-((4-sulfophenyl)azo)phenyl)azo)-, disodium salt
Disodium 7-benzamido-4-hydroxy-3-((4-((4-sulphonatophenyl)azo)phenyl)azo)naphthalene-2-sulphonat
Solaminrot 4B
Direct Red 81 disodium salt
C.I. Direct Red 81
Airedale Red KD
Aizen Primula Red 4BH
Amanil Fast Red 8BL
Amanil Fast Red 8BLW
Belamine Fast Red 8BL
Belamine Fast Red 8 BL
Benzanil Fast Red K
Benzo Fast Red 8BL
Bordeaux EMBL
Calcodur Red 8BL
Chloramine Fast Red K
Chloramine Fast Red 5BL
Chlorantine Fast Red
Chlorantine Fast Red 5B
Chemical Function
Dye
Regulatory Lists
inert_ingredient; non_food_use; Pesticides
banned; Europe; Personal care
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Direct Red 81 allowed in the EU?
Direct Red 81 EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Direct Red 81 do in cosmetics?
Direct Red 81 functions as: Colorant. It is classified as a cosmetic ingredient in our database. CAS number: 2610-11-9.
Is Direct Red 81 used outside cosmetics?
Direct Red 81 also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Direct Red 81 have different safety status in cosmetics vs industrial chemicals?
Direct Red 81 is prohibited in EU cosmetics but has active industrial GHS classifications.
Compliance Tools
Check Direct Red 81 compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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Direct Red 80
Poor
Chemical family
Colorant
DISODIUM GLUCARATE/GLUCONATE/GLUCURONATE/GLYCOLATE/KETOGLUCONATE/OXALATE/TARTRATE/TARTRONATE
Good
Browse nearby
Chelating
DISODIUM SELENITE
Moderate
Browse nearby
Not Reported
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