Is Acetyl Tyrosine safe in cosmetics?
Acetyl Tyrosine has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Acetyl Tyrosine
Also known as: L-Tyrosine, N-acetyl-, Tyrosine, N-acetyl-, L-, (+)-(2S)-2-(Acetylamino)-3-(4-hydroxyphenyl)propanoic acid, (2S)-2-Acetylamino-3-(4-hydroxyphenyl)propanoic acid, Tyr-Excel (+11 more)
INCI: ACETYL TYROSINE
Acetyl Tyrosine (CAS 537-55-3) is a cosmetic cosmetic ingredient functioning as Skin Conditioning, Tanning Agent, Melanogenesis Activator, Antioxidant. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 537-55-3 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Acetyl Tyrosine is classified GHS Danger (H318) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Skin Conditioning, Tanning Agent, Melanogenesis Activator, Antioxidant
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
(2S)-2-acetamido-3-(4-hydroxyphenyl)propanoic acid
InChIKey
CAHKINHBCWCHCF-JTQLQIEISA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
No specific restrictions. Used in cosmetics under standard FDA cosmetic regulations.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Acetyl Tyrosine.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
2 property records from structured ingredient metadata.
amino_acid
{"cas_number": "537-55-3", "ingredient_class": "amino_acid", "source_origin": "synthetic", "molecular_weight_range_Da": "223", "amino_acid_composition_key": "N_acetyl_tyrosine", "charge_at_pH_5_5": "anionic", "water_solubility": "soluble", "oil_solubility": "partially", "film_forming_ability": "poor", "moisture_binding_capacity": "moderate", "NMF_component": "no", "skin_penetration_depth": "epider…
self_tanning
{"cas_number": "537-55-3", "ingredient_class": "tan_accelerator", "tanning_mechanism": "melanin_stimulation", "color_development_onset_hours": "36.0", "full_color_development_hours": "120", "color_duration_days": "14", "color_depth": "adjustable", "undertone": "natural", "color_uniformity": "excellent", "fade_pattern": "even", "DHA_concentration_if_applicable_pct": "0", "erythrulose_concentration_…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Acetyl Tyrosine.
Known Synonyms
L-Tyrosine, N-acetyl-
Tyrosine, N-acetyl-, L-
(+)-(2S)-2-(Acetylamino)-3-(4-hydroxyphenyl)propanoic acid
(2S)-2-Acetylamino-3-(4-hydroxyphenyl)propanoic acid
Tyr-Excel
N-acetyl-L-tyrosine
TYROSINE, (L)-, N-ACETYL-
EINECS 208-671-3
NSC 10853
UNII-DA8G610ZO5
L-Tyrosine, acetyl-
L-N-Acetyl-Tyrosine
L-N-Acetyltyrosine
N-Acetyl-4-hydroxyphenylalanine
N-Acetyl-tyrosine
N-Acetyltyrosine
Chemical Function
Softener and conditioner
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
ACETYL TYROSINE
ChEMBL ID
CHEMBL65543
Frequently Asked Questions
Is Acetyl Tyrosine allowed in the EU?
Acetyl Tyrosine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Acetyl Tyrosine do in cosmetics?
Acetyl Tyrosine functions as: Skin Conditioning, Tanning Agent, Melanogenesis Activator, Antioxidant. It is classified as a cosmetic ingredient in our database. CAS number: 537-55-3.
Is Acetyl Tyrosine used outside cosmetics?
Acetyl Tyrosine also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Acetyl Tyrosine have different safety status in cosmetics vs industrial chemicals?
Acetyl Tyrosine is classified GHS Danger (H318) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check Acetyl Tyrosine compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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