What is the NOAEL for N-Acetyl-L-tyrosine?
N-Acetyl-L-tyrosine has 4 NOAEL studies in the database. The lowest reported value is DA8G610ZO5 UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
N-Acetyl-L-tyrosine
Also known as: L-Tyrosine, N-acetyl-, Tyrosine, N-acetyl-, L-, (+)-(2S)-2-(Acetylamino)-3-(4-hydroxyphenyl)propanoic acid, (2S)-2-Acetylamino-3-(4-hydroxyphenyl)propanoic acid, Tyr-Excel (+11 more)
CAS 537-55-3
N-Acetyl-L-tyrosine (CAS 537-55-3) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
Cross-Vertical Regulatory Divergence
N-Acetyl-L-tyrosine is classified GHS Danger (H318) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
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noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
22 fields
Name
N-Acetyl-L-tyrosine
CAS Number
537-55-3
DTXSID
DTXSID7046045
Molecular Formula
C11H13NO4
InChI Key
CAHKINHBCWCHCF-JTQLQIEISA-N
Monoisotopic Mass
223.084458
Synonyms
L-Tyrosine, N-acetyl-Tyrosine, N-acetyl-, L-(+)-(2S)-2-(Acetylamino)-3-(4-hydroxyphenyl)propanoic acid(2S)-2-Acetylamino-3-(4-hydroxyphenyl)propanoic acidTyr-ExcelTYROSINE, (L)-, N-ACETYL-EINECS 208-671-3NSC 10853UNII-DA8G610ZO5L-Tyrosine, acetyl-L-N-Acetyl-TyrosineL-N-Acetyltyrosine
Functional Uses
Industrial and product-use categories associated with this substance.
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EPA CPDat
6 records
Softener and conditioner
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
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NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| DA8G610ZO5 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| DA8G610ZO5 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| DA8G610ZO5 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| DA8G610ZO5 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Other
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
ACETYL TYROSINE
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
2
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
1 food-safety record found.
View full food safety profile →Frequently Asked Questions
Is N-Acetyl-L-tyrosine used in cosmetics?
Yes, N-Acetyl-L-tyrosine is also indexed as a cosmetic ingredient under the name Acetyl Tyrosine. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for N-Acetyl-L-tyrosine come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.
Does N-Acetyl-L-tyrosine have different safety status in cosmetics vs industrial chemicals?
N-Acetyl-L-tyrosine is classified GHS Danger (H318) in the chemicals database but is allowed in EU cosmetics.
Is N-Acetyl-L-tyrosine used outside industrial chemicals?
N-Acetyl-L-tyrosine also appears in cosmetics, pharmaceutical, food safety databases.