Is 4,4'-Diaminodiphenylamine Sulfate safe in cosmetics?
4,4'-Diaminodiphenylamine Sulfate has a safety rating of "POOR" in our database. EU status: prohibited. US status: permitted.
Poor
Cosmetic Ingredient
4,4'-Diaminodiphenylamine Sulfate
Also known as: 1,3-Benzenediol, 4,6-diamino-, hydrochloride (1:2), Resorcinol, 4,6-diamino-, dihydrochloride, 1,3-Benzenediol, 4,6-diamino-, dihydrochloride, 4,6-Diamino-1,3-benzenediol dihydrochloride, 4,6-Diaminoresorcin dihydrochloride (+3 more)
INCI: 4,4'-DIAMINODIPHENYLAMINE SULFATE
4,4'-Diaminodiphenylamine Sulfate (CAS 16523-31-2) is a cosmetic cosmetic ingredient functioning as Hair Dye (oxidative). EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 16523-31-2 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
4,4'-Diaminodiphenylamine Sulfate is prohibited in EU cosmetics but has active industrial GHS classifications (H315, H319, H335, H341).
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Hair Dye (oxidative)
Safety Rating
POOR
Chemistry & Identifiers
IUPAC Name
4,6-diaminobenzene-1,3-diol;dihydrochloride
InChIKey
KUMOYHHELWKOCB-UHFFFAOYSA-N
Regulatory Status
EU EU Status
prohibited
US US Status
permitted
US Notes
Same as parent compound — coal tar hair dye exemption with labeling requirements
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for 4,4'-Diaminodiphenylamine Sulfate.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for 4,4'-Diaminodiphenylamine Sulfate.
Known Synonyms
1,3-Benzenediol, 4,6-diamino-, hydrochloride (1:2)
Resorcinol, 4,6-diamino-, dihydrochloride
1,3-Benzenediol, 4,6-diamino-, dihydrochloride
4,6-Diamino-1,3-benzenediol dihydrochloride
4,6-Diaminoresorcin dihydrochloride
1,3-Diamino-4,6-dihydroxybenzene dihydrochloride
6-Dihydroxy-m-phenylenediamine dihydrochloride
4,6-Diamino-1,3-dihydroxybenzene dihydrochloride
Frequently Asked Questions
Is 4,4'-Diaminodiphenylamine Sulfate allowed in the EU?
4,4'-Diaminodiphenylamine Sulfate EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does 4,4'-Diaminodiphenylamine Sulfate do in cosmetics?
4,4'-Diaminodiphenylamine Sulfate functions as: Hair Dye (oxidative). It is classified as a cosmetic ingredient in our database. CAS number: 16523-31-2.
Is 4,4'-Diaminodiphenylamine Sulfate used outside cosmetics?
4,4'-Diaminodiphenylamine Sulfate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does 4,4'-Diaminodiphenylamine Sulfate have different safety status in cosmetics vs industrial chemicals?
4,4'-Diaminodiphenylamine Sulfate is prohibited in EU cosmetics but has active industrial GHS classifications (H315, H319, H335, H341).
Compliance Tools
Check 4,4'-Diaminodiphenylamine Sulfate compliance across multiple jurisdictions:
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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