Is 2,4-Dimethylpyridine safe in cosmetics?
2,4-Dimethylpyridine has a safety rating of "POOR" in our database. EU status: permitted. US status: restricted.
Poor
Cosmetic Ingredient
2,4-Dimethylpyridine
Also known as: 5-20-06-00019, BRN 0001506, alpha,gamma-Dimethylpyridine, EINECS 203-586-8, UNII-83903UJ0WW
INCI: 2,4-DIMETHYLPYRIDINE (COMMON NAME: 2,4-LUTIDINE)
2,4-Dimethylpyridine (CAS 108-47-4) is a cosmetic cosmetic ingredient functioning as Fragrance (limited); primarily an industrial solvent and chemical intermediate. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 108-47-4 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance (limited); primarily an industrial solvent and chemical intermediate
Safety Rating
POOR
Chemistry & Identifiers
IUPAC Name
2,4-dimethylpyridine
InChIKey
JYYNAJVZFGKDEQ-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
restricted
US Notes
Not specifically restricted; must meet general cosmetic safety requirements under FD\&C Act
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for 2,4-Dimethylpyridine.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Intermediate
Tonnage Band
Intermediate use only
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (2)
JECFA Number
2151
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
2,4-DIMETHYLPYRIDINE | 2012 | No safety concern at current levels of intake when used as a flavouring agent (temporary pending receipt of additional toxicological data) | TRS 974-JECFA 76 | FAS 67 JECFA 76
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for 2,4-Dimethylpyridine.
Regulatory Flags
fragrance-component
ifra_fragrance
fda_food_additive
jecfa_safe
Known Synonyms
5-20-06-00019
BRN 0001506
alpha,gamma-Dimethylpyridine
EINECS 203-586-8
UNII-83903UJ0WW
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
IFRA Transparency
Europe
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL5286019
Frequently Asked Questions
Is 2,4-Dimethylpyridine allowed in the EU?
2,4-Dimethylpyridine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does 2,4-Dimethylpyridine do in cosmetics?
2,4-Dimethylpyridine functions as: Fragrance (limited); primarily an industrial solvent and chemical intermediate. It is classified as a cosmetic ingredient in our database. CAS number: 108-47-4.
Is 2,4-Dimethylpyridine used outside cosmetics?
2,4-Dimethylpyridine also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check 2,4-Dimethylpyridine compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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