What is the NOAEL for 2,4-Dimethylpyridine?
2,4-Dimethylpyridine has 6 NOAEL studies in the database. The lowest reported value is 83903UJ0WW UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
2,4-Dimethylpyridine
Also known as: 5-20-06-00019, BRN 0001506, alpha,gamma-Dimethylpyridine, EINECS 203-586-8, UNII-83903UJ0WW
CAS 108-47-4
2,4-Dimethylpyridine (CAS 108-47-4) is a chemical substance. Key regulatory status: REACH registered, 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
6
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
11 fields
Name
2,4-Dimethylpyridine
CAS Number
108-47-4
DTXSID
DTXSID2051556
Molecular Formula
C7H9N
InChI Key
JYYNAJVZFGKDEQ-UHFFFAOYSA-N
Monoisotopic Mass
107.073499
Synonyms
5-20-06-00019BRN 0001506alpha,gamma-DimethylpyridineEINECS 203-586-8UNII-83903UJ0WW
Functional Uses
Industrial and product-use categories associated with this substance.
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EPA CPDat
4 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| Europe | European Commission | Fl@vis |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 6 of 6 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 83903UJ0WW | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 83903UJ0WW | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =200 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =37 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_EFSA |
| =37 | mg/kg bw/day | NOAEL | oral: gavage | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| =37 | mg/kg bw/day | NOAEL | oral: gavage | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
Showing 6 of 6 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 2,4-dimethylpyridine | 203-586-8 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
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CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL5286019
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
1
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
ADI: No safety concern at current levels of intake when used as a flavouring agent (temporary pending receipt of additional toxicological data) mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include 2,4-Dimethylpyridine?
2,4-Dimethylpyridine appears on 3 regulatory/inventory lists including IFRA Transparency, Europe, food_additive; Substances Added to Food (formerly EAFUS) (2/2019). Source: EPA CPDat.
Is 2,4-Dimethylpyridine used in cosmetics?
Yes, 2,4-Dimethylpyridine is also indexed as a cosmetic ingredient under the name 2,4-Dimethylpyridine. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 2,4-Dimethylpyridine come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is 2,4-Dimethylpyridine used outside industrial chemicals?
2,4-Dimethylpyridine also appears in cosmetics, pharmaceutical, food safety, cannabis databases.