Is Tetramethyl-1-hexadecen-3-ol safe in cosmetics?
Tetramethyl-1-hexadecen-3-ol has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Tetramethyl-1-hexadecen-3-ol
Also known as: 1-Hexadecen-3-ol, 3,7,11,15-tetramethyl-, EINECS 208-008-8, 2,6,10,14-Tetramethylhexadec-15-en-14-ol, 2,6,10-Trimethyl-14-vinylpentadecan-14-ol, UNII-A831ZI6VIM
INCI: TETRAMETHYL-1-HEXADECEN-3-OL
Tetramethyl-1-hexadecen-3-ol (CAS 505-32-8) is a cosmetic cosmetic ingredient functioning as Fragrance (Parfum). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 505-32-8 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Tetramethyl-1-hexadecen-3-ol is classified GHS CMR hazard (H315, H400, H410, H320, H361) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu status; Chemicals: ghs classifications.signal word/hazard statement code
Function
Fragrance (Parfum)
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
3,7,11,15-tetramethylhexadec-1-en-3-ol
InChIKey
KEVYVLWNCKMXJX-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted for cosmetic use as fragrance ingredient
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Tetramethyl-1-hexadecen-3-ol.
Calculate MoS for your specific formulation with the MoS Calculator.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 6750 | - | - |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (1)
Endocrine Disruptors
Potential endocrine disrupting compound
Source: NORMAN Suspect List Exchange
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for Tetramethyl-1-hexadecen-3-ol.
Regulatory Flags
fragrance-component
ifra_fragrance
Known Synonyms
1-Hexadecen-3-ol, 3,7,11,15-tetramethyl-
EINECS 208-008-8
2,6,10,14-Tetramethylhexadec-15-en-14-ol
2,6,10-Trimethyl-14-vinylpentadecan-14-ol
UNII-A831ZI6VIM
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
pharmaceutical
IFRA Transparency
Europe
consumer_product
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL453797
Frequently Asked Questions
Is Tetramethyl-1-hexadecen-3-ol allowed in the EU?
Tetramethyl-1-hexadecen-3-ol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Tetramethyl-1-hexadecen-3-ol do in cosmetics?
Tetramethyl-1-hexadecen-3-ol functions as: Fragrance (Parfum). It is classified as a cosmetic ingredient in our database. CAS number: 505-32-8.
Is Tetramethyl-1-hexadecen-3-ol used outside cosmetics?
Tetramethyl-1-hexadecen-3-ol also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Tetramethyl-1-hexadecen-3-ol have different safety status in cosmetics vs industrial chemicals?
Tetramethyl-1-hexadecen-3-ol is classified GHS CMR hazard (H315, H400, H410, H320, H361) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check Tetramethyl-1-hexadecen-3-ol compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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