Is Dithiodiglycolic Acid safe in cosmetics?
Dithiodiglycolic Acid has a safety rating of "MODERATE" in our database. EU status: restricted. US status: restricted.
Moderate
Cosmetic Ingredient
Dithiodiglycolic Acid
INCI: DITHIODIGLYCOLIC ACID
Dithiodiglycolic Acid (CAS 505-73-7) is a cosmetic cosmetic ingredient functioning as Reducing agent / depilatory agent (oxidized disulfide dimer of thioglycolic. EU Regulation 1223/2009 status: restricted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 505-73-7 →
Auto-generated CPSR Part A draft with source citations
Function
Reducing agent / depilatory agent (oxidized disulfide dimer of thioglycolic acid)
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
2-(carboxymethyldisulfanyl)acetic acid
InChIKey
DLLMHEDYJQACRM-UHFFFAOYSA-N
Regulatory Status
EU EU Status
restricted
US US Status
restricted
US Notes
Permitted with restrictions — thioglycolate-based depilatories are regulated; 21 CFR 700 does not explicitly list dithiodiglycolic acid but functional equivalence applies
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Dithiodiglycolic Acid.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Reducing agent
Expert Verdict
Expert safety assessment and concern-level summary for Dithiodiglycolic Acid.
Regulatory Flags
potential-allergen
Chemical Function
Reducing agent
Regulatory Lists
Canada; Personal care; Substances in PCP - Canada (4/2014)
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL1611974
Frequently Asked Questions
Is Dithiodiglycolic Acid allowed in the EU?
Dithiodiglycolic Acid EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Dithiodiglycolic Acid do in cosmetics?
Dithiodiglycolic Acid functions as: Reducing agent / depilatory agent (oxidized disulfide dimer of thioglycolic acid). It is classified as a cosmetic ingredient in our database. CAS number: 505-73-7.
Is Dithiodiglycolic Acid used outside cosmetics?
Dithiodiglycolic Acid also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Dithiodiglycolic Acid compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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