Is Thiodiglycolic Acid safe in cosmetics?
Thiodiglycolic Acid has a safety rating of "MODERATE" in our database. EU status: restricted. US status: restricted.
Moderate
Cosmetic Ingredient
Thiodiglycolic Acid
Also known as: Acetic acid, dithiodi-, Dithiodiacetic acid, 2,2'-Dithiodiacetic acid, Dithioglycolic acid, EINECS 208-019-8 (+3 more)
INCI: THIODIGLYCOLIC ACID (ALSO KNOWN AS DITHIOGLYCOLIC ACID / MERCAPTODIACETIC ACID)
Thiodiglycolic Acid (CAS 505-73-7) is a cosmetic cosmetic ingredient functioning as Reducing agent. EU Regulation 1223/2009 status: restricted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 505-73-7 →
Auto-generated CPSR Part A draft with source citations
Function
Reducing agent
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
2-(carboxymethyldisulfanyl)acetic acid
InChIKey
DLLMHEDYJQACRM-UHFFFAOYSA-N
Regulatory Status
EU EU Status
restricted
US US Status
restricted
US Notes
Not specifically restricted; no CIR review found
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Thiodiglycolic Acid.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Reducing agent
Expert Verdict
Expert safety assessment and concern-level summary for Thiodiglycolic Acid.
Known Synonyms
Acetic acid, dithiodi-
Dithiodiacetic acid
2,2'-Dithiodiacetic acid
Dithioglycolic acid
EINECS 208-019-8
NSC 54088
Thioglycolate disulfide
UNII-7ZZ0LAL4TI
Chemical Function
Reducing agent
Regulatory Lists
Canada; Personal care; Substances in PCP - Canada (4/2014)
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL1611974
Frequently Asked Questions
Is Thiodiglycolic Acid allowed in the EU?
Thiodiglycolic Acid EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Thiodiglycolic Acid do in cosmetics?
Thiodiglycolic Acid functions as: Reducing agent. It is classified as a cosmetic ingredient in our database. CAS number: 505-73-7.
Is Thiodiglycolic Acid used outside cosmetics?
Thiodiglycolic Acid also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Thiodiglycolic Acid compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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