Is POLY METHYL STYRENE ISOPROPANOL KETONE safe in cosmetics?
POLY METHYL STYRENE ISOPROPANOL KETONE has a safety rating of "GOOD" in our database. EU status: permitted. 3 toxicological study endpoint(s) are available in our database.
POLY METHYL STYRENE ISOPROPANOL KETONE
Also known as: Oligo[2-hydroxy-2-methyl-1-[4-(1-methylvinyl)phenyl]propanone] -, EC No.: 402-990-3, (1-Methylethenyl)benzene homopolymer, ar-(2-hydroxy-2-methyl-1-oxopropyl) derivs.
POLY METHYL STYRENE ISOPROPANOL KETONE (CAS 163702-01-0) is a cosmetic cosmetic ingredient functioning as Light Stabilizer. Reported NOAEL =10 mg/kg bw/day in Rat (ToxValDB_ECHA_IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 163702-01-0 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
POLY METHYL STYRENE ISOPROPANOL KETONE is classified GHS Danger (H361, H372, H413) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Light Stabilizer
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
Not specifically regulated
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Toxicological Studies
3 study endpoints found for POLY METHYL STYRENE ISOPROPANOL KETONE. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =10 mg/kg bw/day | oral | Rat | reproduction developmental | ToxValDB_ECHA_IUCLID |
| NOAEL | =40 mg/kg bw/day | oral | Rat | short-term | ToxValDB_ECHA_IUCLID |
| NOAEL | =250 mg/kg bw/day | oral | Rat | developmental | ToxValDB_ECHA_IUCLID |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Photosensitizers
Stabilizing agent
Expert Verdict
Expert safety assessment and concern-level summary for POLY METHYL STYRENE ISOPROPANOL KETONE.
Regulatory Flags
cosing-sourced
eu-permitted
needs-enrichment
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to POLY METHYL STYRENE ISOPROPANOL KETONE by CAS number or substance name.
Studies
3
Lowest NOAEL
10 mg/kg bw/day
Highest NOAEL
250 mg/kg bw/day
ToxValDB_ECHA_IUCLID
Known Synonyms
Oligo[2-hydroxy-2-methyl-1-[4-(1-methylvinyl)phenyl]propanone] -
EC No.: 402-990-3
(1-Methylethenyl)benzene homopolymer, ar-(2-hydroxy-2-methyl-1-oxopropyl) derivs.
Chemical Function
Stabilizing agent
Photosensitizers
Frequently Asked Questions
Is POLY METHYL STYRENE ISOPROPANOL KETONE allowed in the EU?
POLY METHYL STYRENE ISOPROPANOL KETONE EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does POLY METHYL STYRENE ISOPROPANOL KETONE do in cosmetics?
POLY METHYL STYRENE ISOPROPANOL KETONE functions as: Light Stabilizer. It is classified as a cosmetic ingredient in our database. CAS number: 163702-01-0.
What is the NOAEL for POLY METHYL STYRENE ISOPROPANOL KETONE?
The NOAEL (No Observed Adverse Effect Level) for POLY METHYL STYRENE ISOPROPANOL KETONE is =10 mg/kg bw/day based on a reproduction developmental study via oral route in Rat. A total of 3 study endpoints are available. Source: ToxValDB_ECHA_IUCLID.
Is POLY METHYL STYRENE ISOPROPANOL KETONE used outside cosmetics?
POLY METHYL STYRENE ISOPROPANOL KETONE also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does POLY METHYL STYRENE ISOPROPANOL KETONE have different safety status in cosmetics vs industrial chemicals?
POLY METHYL STYRENE ISOPROPANOL KETONE is classified GHS Danger (H361, H372, H413) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
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Ingredient Decoder
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Substance Compliance
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MoS Calculator
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