NOAEL Data REACH Registered Cosmetic Ingredient

Benzene, (1-methylethenyl)-, homopolymer, ar-(2-hydroxy-2-methyl-1-oxopropyl) derivs.

Also known as: Oligo[2-hydroxy-2-methyl-1-[4-(1-methylvinyl)phenyl]propanone] -, EC No.: 402-990-3, (1-Methylethenyl)benzene homopolymer, ar-(2-hydroxy-2-methyl-1-oxopropyl) derivs.

CAS 163702-01-0

Benzene, (1-methylethenyl)-, homopolymer, ar-(2-hydroxy-2-methyl-1-oxopropyl) derivs. (CAS 163702-01-0) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, ECHA REACH.

View cosmetic safety profile for POLY METHYL STYRENE ISOPROPANOL KETONE →

Cross-Vertical Regulatory Divergence

Benzene, (1-methylethenyl)-, homopolymer, ar-(2-hydroxy-2-methyl-1-oxopropyl) derivs. is classified GHS Danger (H361, H372, H413) in the chemicals database but is allowed in EU cosmetics.

SOURCE Cross-vertical comparison Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code

SOURCE noael studies public

NOAEL studies

SOURCE chemical inventory jurisdictions

Regulatory lists

SOURCE eu clp annex vi

GHS signal

Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 6 fields

Name

Benzene, (1-methylethenyl)-, homopolymer, ar-(2-hydroxy-2-methyl-1-oxopropyl) derivs.

CAS Number

163702-01-0

DTXSID

DTXSID60108455

Synonyms

Oligo[2-hydroxy-2-methyl-1-[4-(1-methylvinyl)phenyl]propanone] -EC No.: 402-990-3(1-Methylethenyl)benzene homopolymer, ar-(2-hydroxy-2-methyl-1-oxopropyl) derivs.

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 7 records

Stabilizing agentPhotosensitizers

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 6 of 6 studies

Value	Unit	Endpoint	Route	Species	Source
=0.0521	mg/m3	DNEL systemic	inhalation	Human	ToxValDB_GESTIS_DNEL
=1.175	mg/m3	DNEL systemic	inhalation	Human	ToxValDB_GESTIS_DNEL
=10	mg/kg bw/day	NOAEL	oral	Rat	ToxValDB_ECHA_IUCLID
=40	mg/kg bw/day	NOAEL	oral	Rat	ToxValDB_ECHA_IUCLID
=250	mg/kg bw/day	NOAEL	oral	Rat	ToxValDB_ECHA_IUCLID
=10	mg/kg bw/day	NOEL	oral	Rat	ToxValDB_ECHA_IUCLID

Showing 6 of 6 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records

Status	Name	EC Number	Link
Registered	A mixture mainly based on: 2,3-dihydro-6-(2-hydroxy-2-methyl-1-oxopropyl)-1,1,3-trimethyl-3-[4-(2-hydroxy-2-methyl-1-oxopropyl)phenyl]-1H-indene; 2,3-dihydro-5-(2-hydroxy-2-methyl-1-oxopropyl)-1,1,3-trimethyl-3-[4-(2-hydroxy-2-methyl-1-oxopropyl)phenyl]-1H-indene	402-990-3	ECHA overview →

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB

EU Status

permitted

Max

Frequently Asked Questions

What is the NOAEL for Benzene, (1-methylethenyl)-, homopolymer, ar-(2-hydroxy-2-methyl-1-oxopropyl) derivs.?

Benzene, (1-methylethenyl)-, homopolymer, ar-(2-hydroxy-2-methyl-1-oxopropyl) derivs. has 6 NOAEL studies in the database. The lowest reported value is 0.0521 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.

Is Benzene, (1-methylethenyl)-, homopolymer, ar-(2-hydroxy-2-methyl-1-oxopropyl) derivs. used in cosmetics?

Yes, Benzene, (1-methylethenyl)-, homopolymer, ar-(2-hydroxy-2-methyl-1-oxopropyl) derivs. is also indexed as a cosmetic ingredient under the name POLY METHYL STYRENE ISOPROPANOL KETONE. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Benzene, (1-methylethenyl)-, homopolymer, ar-(2-hydroxy-2-methyl-1-oxopropyl) derivs. come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Does Benzene, (1-methylethenyl)-, homopolymer, ar-(2-hydroxy-2-methyl-1-oxopropyl) derivs. have different safety status in cosmetics vs industrial chemicals?

Benzene, (1-methylethenyl)-, homopolymer, ar-(2-hydroxy-2-methyl-1-oxopropyl) derivs. is classified GHS Danger (H361, H372, H413) in the chemicals database but is allowed in EU cosmetics.

Is Benzene, (1-methylethenyl)-, homopolymer, ar-(2-hydroxy-2-methyl-1-oxopropyl) derivs. used outside industrial chemicals?

Benzene, (1-methylethenyl)-, homopolymer, ar-(2-hydroxy-2-methyl-1-oxopropyl) derivs. also appears in cosmetics databases.