Is Menthyl Acetate safe in cosmetics?
Menthyl Acetate has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Menthyl Acetate
Also known as: Menthol, acetate, cis-1,3,trans-1,4-, Cyclohexanol, 5-methyl-2-(1-methylethyl)-, acetate, (1R,2S,5R)-rel-, Cyclohexanol, 5-methyl-2-(1-methylethyl)-, acetate, (1α,2β,5α)-, (+/-)-Menthol acetate, (+/-)-Menthyl acetate (+7 more)
INCI: MENTHYL ACETATE
Menthyl Acetate (CAS 89-48-5) is a cosmetic cosmetic ingredient functioning as Fragrance, Refreshing. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 89-48-5 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance, Refreshing
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
(5-methyl-2-propan-2-ylcyclohexyl) acetate
InChIKey
XHXUANMFYXWVNG-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Allowed - classified GRAS as a flavoring agent (21 CFR 172.515, 182.20; FEMA No. 2668)
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Menthyl Acetate.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (2)
JECFA Number
431
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
MENTHYL ACETATE | 1998 | No safety concern at current levels of intake when used as a flavouring agent | TRS 891-JECFA 51/111 | FAS 42-JECFA 51/381
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Deodorizer
Flavouring and nutrient
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for Menthyl Acetate.
Regulatory Flags
potential-allergen
fragrance-component
ifra_fragrance
fda_food_additive
jecfa_safe
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Menthyl Acetate by CAS number or substance name.
Studies
3
Lowest NOAEL
1250 mg/kg bw/day
Highest NOAEL
1250 mg/kg bw/day
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip
Known Synonyms
Menthol, acetate, cis-1,3,trans-1,4-
Cyclohexanol, 5-methyl-2-(1-methylethyl)-, acetate, (1R,2S,5R)-rel-
Cyclohexanol, 5-methyl-2-(1-methylethyl)-, acetate, (1α,2β,5α)-
(+/-)-Menthol acetate
(+/-)-Menthyl acetate
Cyclohexanol, 5-methyl-2-(1-methylethyl)-, 1-acetate, (1R,2S,5R)-rel-
EC No.: 201-911-8
EINECS 201-911-8
p-Menth-3-yl acetate, dl-
UNII-LF3LEI45OH
rel-(1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexyl acetate
201-911-8
Chemical Function
Deodorizer
Flavouring and nutrient
Fragrance
Regulatory Lists
inert_ingredient; non_food_use; Pesticides
IFRA Transparency
Europe
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
IFRA Transparency
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Menthyl Acetate allowed in the EU?
Menthyl Acetate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Menthyl Acetate do in cosmetics?
Menthyl Acetate functions as: Fragrance, Refreshing. It is classified as a cosmetic ingredient in our database. CAS number: 89-48-5.
Is Menthyl Acetate used outside cosmetics?
Menthyl Acetate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Menthyl Acetate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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