Is D-Pulegone safe in cosmetics?
D-Pulegone has a safety rating of "POOR" in our database. EU status: prohibited. US status: prohibited.
Poor
Cosmetic Ingredient
D-Pulegone
INCI: PULEGONE
D-Pulegone (CAS 89-82-7 (pulegone)) is a cosmetic cosmetic ingredient functioning as Fragrance and flavor component present in mint/pennyroyal-type oils;. EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 89-82-7 (pulegone) →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance and flavor component present in mint/pennyroyal-type oils; characterizing substance in some essential oils
Safety Rating
POOR
Regulatory Status
EU EU Status
prohibited
US US Status
prohibited
US Notes
Pulegone was previously used as a synthetic flavoring and has been removed from the list of approved synthetic flavoring substances in foods for safety reasons. In cosmetics, it is not specifically banned but its hepatotoxicity and carcinogenic potential require rigorous safety justification and very low residual levels when present as an impurity in essential oils.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for D-Pulegone.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
1 property record from structured ingredient metadata.
fragrance_ifra
{"cas_number": "89-82-7", "ifra_amendment_number": "49", "ifra_restriction_type": "Restricted", "ifra_max_use_level_category_1_pct": "0.035", "ifra_max_use_level_category_4_pct": "0.25", "ifra_max_use_level_category_7_pct": "0.10", "ifra_max_use_level_category_11_pct": "0.020", "eu_allergen_declaration_required": "No", "eu_26_allergens_list": "Proposed", "sccs_opinion_available": "Yes", "sensitiza…
Expert Verdict
Expert safety assessment and concern-level summary for D-Pulegone.
Regulatory Flags
essential-oil
fragrance-component
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to D-Pulegone by CAS number or substance name.
Studies
1
Lowest NOAEL
80 mg/kg bw/day
Highest NOAEL
80 mg/kg bw/day
COSMOS_DB
Frequently Asked Questions
Is D-Pulegone allowed in the EU?
D-Pulegone EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does D-Pulegone do in cosmetics?
D-Pulegone functions as: Fragrance and flavor component present in mint/pennyroyal-type oils; characterizing substance in some essential oils. It is classified as a cosmetic ingredient in our database. CAS number: 89-82-7 (pulegone).
Compliance Tools
Check D-Pulegone compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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