Is Isoeugenol Acetate safe in cosmetics?
Isoeugenol Acetate has a safety rating of "POOR" in our database. EU status: restricted. US status: permitted.
Poor
Cosmetic Ingredient
Isoeugenol Acetate
Also known as: 2-Methoxy-4-prop-1-enylphenyl acetate, 1-Acetoxy-2-methoxy-4-(1-propenyl)benzene, Acetisoeugenol, 4-Acetoxy-3-methoxy-1-propenylbenzene, 4-Acetoxy-3-methoxy-1-(1-propen-1-yl)benzene (+9 more)
INCI: ISOEUGENYL ACETATE
Isoeugenol Acetate (CAS 93-29-8) is a cosmetic cosmetic ingredient functioning as Perfuming, Fragrance. EU Regulation 1223/2009 status: restricted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and food safety data.
View industrial chemical safety profile for CAS 93-29-8 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Isoeugenol Acetate is classified GHS CMR hazard (H317, H351) in the chemicals database but is restricted in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Perfuming, Fragrance
Safety Rating
POOR
Chemistry & Identifiers
IUPAC Name
(2-methoxy-4-prop-1-enylphenyl) acetate
InChIKey
IUSBVFZKQJGVEP-UHFFFAOYSA-N
Regulatory Status
EU EU Status
restricted
US US Status
permitted
US Notes
RIFM assessed; recognized contact sensitizer; IFRA restricts use levels by product category; disclose on label above threshold concentrations
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Isoeugenol Acetate.
Calculate MoS for your specific formulation with the MoS Calculator.
IFRA Concentration Limits (12 Product Categories)
International Fragrance Association standards per product category. Restriction: Restriction. Effective: 2024-01-01.
| Category | Max % | Category | Max % |
|---|---|---|---|
| 1 (Lip products) | – | 7a (Deodorant – not spray) | – |
| 2 (Body spray) | – | 7b (Deodorant spray) | – |
| 3 (Body cream) | – | 8 (Face cream) | – |
| 4 (Fine fragrance) | – | 9 (Soap) | – |
| 5a (Body lotion) | – | 10a (Household – non-spray) | – |
| 5b (Face cream leave-on) | – | 10b (Household – spray) | – |
| 5c (Hand cream) | – | 11a (Intimate – leave-on) | – |
| 5d (Baby cream) | – | 11b (Intimate – rinse) | – |
| 6 (Mouthwash) | – | 12 (Not for consumer exposure) | – |
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (3)
JECFA Number
1262
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
1-ACETOXY-2-METHOXY-4-(1-PROPENYL)BENZENE | 2003 | No safety concern at current levels of intake when used as a flavouring agent | TRS 922-JECFA 61/96 | FAS 52-JECFA 61/389
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
ISOEUGENYL ACETATE | 2003 | No safety concern at current levels of intake when used as a flavouring agent | TRS 922-JECFA 61/96 | FAS 52-JECFA 61/389
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (3)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for Isoeugenol Acetate.
Regulatory Flags
fragrance-allergen
sensitizer
eu-restricted
annex-III
avoid-leave-on
ifra_fragrance
fda_food_additive
Known Synonyms
2-Methoxy-4-prop-1-enylphenyl acetate
1-Acetoxy-2-methoxy-4-(1-propenyl)benzene
Acetisoeugenol
4-Acetoxy-3-methoxy-1-propenylbenzene
4-Acetoxy-3-methoxy-1-(1-propen-1-yl)benzene
Acetyl isoeugenol
Acetylisoeugenol
EINECS 202-236-1
FEMA No. 2470
Isoeugenol, acetate
2-Methoxy-4-propenylphenyl acetate
2-Methoxy-4-(1-propenyl)phenyl acetate
NSC 46121
UNII-9DF21GI8W6
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
Europe
IFRA Transparency
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
consumer_product
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in food safety data.
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
ISOEUGENYL ACETATE
ADI
No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
Food Category
flavoring
Frequently Asked Questions
Is Isoeugenol Acetate allowed in the EU?
Isoeugenol Acetate EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Isoeugenol Acetate do in cosmetics?
Isoeugenol Acetate functions as: Perfuming, Fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 93-29-8.
Is Isoeugenol Acetate used outside cosmetics?
Isoeugenol Acetate also appears in industrial chemical safety and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Isoeugenol Acetate have different safety status in cosmetics vs industrial chemicals?
Isoeugenol Acetate is classified GHS CMR hazard (H317, H351) in the chemicals database but is restricted in EU cosmetics.
Compliance Tools
Check Isoeugenol Acetate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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