Good UV Filter / Sunscreen NOAEL Data

Ethylhexyl Triazone

Also known as: Tris(2-ethylhexyl)-4,4',4''-(1,3,5-triazine-2,4,6-triyltriimino)tribenzoate

INCI: ETHYLHEXYL TRIAZONE

Ethylhexyl Triazone (CAS 88122-99-0) is a cosmetic uv filter / sunscreen functioning as UV Filter. Reported NOAEL =1000 mg/kg bw/day in Rat (ECHA); EU Regulation 1223/2009 status: permitted, max 5%. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.

View industrial chemical safety profile for CAS 88122-99-0 →

Auto-generated CPSR Part A draft with source citations
Function
UV Filter
Safety Rating
GOOD

Chemistry & Identifiers

EC Number
402-070-1

Regulatory Status

EU EU Status permitted
EU Max Conc. 5%
US US Status permitted

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Ethylhexyl Triazone.

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Ethylhexyl Triazone. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL =1000 mg/kg bw/day oral Rat developmental ECHA

Endocrine Disruptor Evidence (Expanded)

Cross-referenced EDC classifications, mechanism data, and dose-response evidence from EDLists, SIN List, and cosmetic-specific detail sources.

Cosmetic-Specific Mechanism
Category: UV filter
Receptor targets: none confirmed
LOEC: N/A
EU status: allowed (max 5%)

no ER/AR activity

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Full
Tonnage Band
1,000 - 10,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No

EU CosIng Annex Listing

European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.

Annex VI — Permitted UV Filters
Max: 5%

Expanded Jurisdictional Detail

Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.

KR Korea MFDS Annex 2 (Restricted)
Category: UV Filter. Max: 5%.
SA Saudi SFDA (VI - UV Filters)
Max: 0.05.
JPKR Japan/Korea Cosmetics
Korea (Restricted): max 5%
BRIN Brazil/India Cosmetics
India: Permitted UV Filter · max 0.05
Additional Jurisdictional Restrictions (5)
Jurisdiction Status Max % Product Type
CN permitted_uv_filter 5 All cosmetics
IN permitted_uv_filter 5.0 sunscreen and other cosmetic products
GCC restricted 5.0 Sunscreen products
BR permitted_uv_filter 5 Sunscreen products
ASEAN permitted_uv_filter 5% -

Additional Ingredient Properties

3 property records from structured ingredient metadata.

anti_pollution
{"cas_number": "88122-99-0", "ingredient_class": "blue_light_filter", "primary_mechanism": "film_forming_barrier", "pollution_types_targeted": "blue_light_HEV/UV_B", "IR_A_protection": "no", "visible_light_protection": "no", "digital_screen_protection_claim": "no", "PAH_neutralization": "no", "ozone_protection": "no", "mitochondrial_protection": "no", "Nrf2_activation": "no", "AhR_pathway_modulati…
baby_pediatric
{"cas_number": "88122-99-0", "ingredient_class": "sunscreen_baby", "pediatric_safety_rating": "acceptable", "minimum_age_months": "12", "neonatal_safe": "no", "premature_infant_safe": "insufficient_data", "skin_barrier_maturity_consideration": "Uvinul T 150", "transepidermal_absorption_risk_pediatric": "low", "systemic_exposure_concern_pediatric": "low", "dose_per_kg_body_weight_concern": "Sunscre…
sunscreen_uv
{"cas_number": "88122-99-0", "uv_filter_type": "organic_UVB", "chemical_class": "triazine", "absorption_spectrum_nm_range": "290-315", "peak_absorption_wavelength_nm": "314", "molar_extinction_coefficient": "32000", "critical_wavelength_nm": "320", "UVA_PF": "2-3", "SPF_contribution_per_percent": "10.5", "photostability_rating": "photostable", "photodegradation_half_life_hours": ">15", "photostabi…

Function Categories & List Membership

Cosmetic/Chemical Function Categories
UV stabilizer
Regulatory List Membership (2)
EU Regulated in Personal Care EU CosIng Cosmetics Ingredient Database

Expert Verdict

Expert safety assessment and concern-level summary for Ethylhexyl Triazone.

Regulatory Flags

eu_cosing_listed

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to Ethylhexyl Triazone by CAS number or substance name.

Studies
1
Lowest NOAEL
1000 mg/kg bw/day
Highest NOAEL
1000 mg/kg bw/day
ECHA

Known Synonyms

Tris(2-ethylhexyl)-4,4',4''-(1,3,5-triazine-2,4,6-triyltriimino)tribenzoate

Chemical Function

UV stabilizer

Regulatory Lists

Europe; Personal care Canada; pharmaceutical

Australian Status

AICIS status: listed

Cross-Vertical Safety Context

Same-CAS public records found in pharmaceutical data.

SOURCE ChEMBL / DrugCentral / FAERS DB_PHARMA CAS match

Pharmaceutical Data

Same-CAS rows from the pharmaceutical spoke database.

ChEMBL ID
CHEMBL4462531
View full pharmaceutical profile →

Frequently Asked Questions

Is Ethylhexyl Triazone safe in cosmetics?

Ethylhexyl Triazone has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted. 1 toxicological study endpoint(s) are available in our database.

Is Ethylhexyl Triazone allowed in the EU?

Ethylhexyl Triazone EU regulatory status: permitted. Maximum allowed concentration: 5%. This is based on EU Regulation 1223/2009 and its amendments.

What does Ethylhexyl Triazone do in cosmetics?

Ethylhexyl Triazone functions as: UV Filter. It is classified as a UV Filter / Sunscreen in our database. CAS number: 88122-99-0.

What is the NOAEL for Ethylhexyl Triazone?

The NOAEL (No Observed Adverse Effect Level) for Ethylhexyl Triazone is =1000 mg/kg bw/day based on a developmental study via oral route in Rat. Source: ECHA.

Is Ethylhexyl Triazone used outside cosmetics?

Ethylhexyl Triazone also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

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Skin Conditioning, Skin Conditioning ...
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Good Similar safety
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(ANGELICA KEISKEI/CHRYSANTHEMUM ZAWADSKII) LEAF/STEM/CINNAMOMUM CASSIA BARK/TRICHOSANTES KIRILOWII FRUIT/ULMUS DAVIDIANA BARK/ROOT/(PAEONIA JAPONICA/BUPLEURUM FALCATUM/POLYGALA TENUIFOLIA ROOT)/VISCUS ALBUM STEM EXTRACT
Good Similar safety
Anti-seborrheic, Anti-sebum, Antioxid...
(APPLE/CITRUS JUNOS/LENTIL/PEAR/PUMPKIN/STRAWBERRY/TOMATO FRUIT)/CORN KERNEL/(ARCTIUM LAPPA/BRASSICA OLERACEA ACEPHALA/CABBAGE/CAMELLIA SINENSIS/MORINGA OLEIFERA/RADISH/SPINACH LEAF)/(SORGHUM BICOLOR LEAF/STEM)/OAT MEAL/POTATO PULP/(CARROT/NELUMBO NUCIFERA/RADISH/WILD YAM ROOT)/(AMARANTHUS HYPOCHONDRIACUS/CASHEW/CICER ARIETINUM/COIX LACRYMA-JOBI MA-YUEN /MACADAMIA TERNIFOLIA/PHASEOLUS ANGULARIS/PISTACIA VERA/RHYNCHOSIA NULUBILIS/RICE/SESAME/SETARIA ITALICA/SOYBEAN/SWEET ALMOND/WHEAT SEED)/HORDEUM VULGARE SPROUT/CYPERUS ESCULENTUS TUBER/ARTEMISIA PRINCEPS/BROCCOLI/CHENOPODIUM QUINOA/ENTEROMORPHA COMPRESSA/HORDEUM VULGARE/IPOMOEA BATATAS/LAMINARIA JAPONICA/LENTINUS EDODES/PLEUROTUS OSTREATUS/PORPHYRA TENERA/UNDARIA PINNATIFIDA EXTRACT
Good Similar safety
Antioxidant
Ethylhexyl Triazone
Good Chemical family
UV Filter (UVB, 280–320 nm absorption)
ETHOXY-METHOXYMETHYL-PHENOL
Good Browse nearby
Perfuming
ETHOXYDIGLYCOL ACETATE
Good Browse nearby
Solvent

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