Good Surfactant Sensitization Data

Cocamide MEA

Also known as: EINECS 268-770-2, UNII-C80684146D

INCI: COCAMIDE MEA

Cocamide MEA (CAS 68140-00-1) is a cosmetic surfactant functioning as Surfactant. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.

View industrial chemical safety profile for CAS 68140-00-1 →

Auto-generated CPSR Part A draft with source citations
Function
Surfactant
Safety Rating
GOOD

Chemistry & Identifiers

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes CIR: SQ

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Cocamide MEA.

Calculate MoS for your specific formulation with the MoS Calculator.

Sensitization Profile

Contact sensitization data for Cocamide MEA based on clinical patch test studies and IFRA standards.

Sensitization Rate
low
Allergen Class
surfactant
EU Allergen Listed
no
Patch Test Positive Rate
0.5%
Cross-reactivity Group
amidoamine-group
Reaction Type
contact-dermatitis

Source: NACDG; IVDK; ESSCA

Typical Use Concentrations

Reported concentration ranges per product category from SCCS/CIR/industry sources.

Product Category Typical Range Max Reported Source
Shampoo 1–3 5 CIR/VCRP

Additional Ingredient Properties

10 property records from structured ingredient metadata.

allergen_detail
{"eu_allergen_listed": "no", "allergen_class": "surfactant", "cross_reactivity_group": "amidoamine-group", "patch_test_frequency_pct": "0.5", "sensitization_rate": "low", "common_reaction_type": "contact-dermatitis", "ifra_restricted": "no", "source": "NACDG; IVDK; ESSCA"}
baby_pediatric
{"cas_number": "CAS-14836", "ingredient_class": "cleanser_baby", "pediatric_safety_rating": "good", "minimum_age_months": "3", "neonatal_safe": "no", "premature_infant_safe": "insufficient_data", "skin_barrier_maturity_consideration": "Mild derivative surfactant", "transepidermal_absorption_risk_pediatric": "low", "systemic_exposure_concern_pediatric": "low", "dose_per_kg_body_weight_concern": "Su…
concentration
{"min_concentration_pct": "1.0", "max_concentration_pct": "5.0", "typical_concentration_pct": "3.0", "product_type": "Body Wash", "function_at_concentration": "Foam booster", "source": "CIR Safety Assessment"}
cost_pricing
{"cost_tier": "budget", "estimated_cost_per_kg_usd_low": "12", "estimated_cost_per_kg_usd_high": "22", "natural_premium_markup_pct": "18", "organic_certified_premium_pct": "35", "supply_chain_volatility": "low", "primary_source_region": "Malaysia/Indonesia", "synthetic_vs_natural_cost_ratio": "1.8", "bulk_discount_threshold_kg": "200", "seasonal_price_variation": "low", "commodity_or_specialty": "…
ecotoxicity
{"biodegradable": "partial", "biodegradation_days": "90-180", "bioaccumulative": "yes", "aquatic_toxicity_level": "moderate", "coral_reef_safe": "unknown", "marine_toxicity": "moderate toxicity", "freshwater_toxicity": "bioaccumulative", "endocrine_disruptor": "suspected", "persistent_organic_pollutant": "no", "microplastic": "no", "nano_particle": "no", "hawaii_banned": "no", "eu_restricted_envir…
emulsion_hlb
{"hlb_value": "13.5", "hlb_required_as_emulsifier": "yes", "emulsifier_type": "o_w", "critical_packing_parameter": "0.23-0.35", "emulsion_stabilization_mechanism": "steric_stabilization", "co_emulsifier_pairs": "cetyl_alcohol,glyceryl_cocoate", "optimal_oil_phase_pct": "5-15", "optimal_water_phase_pct": "85-95", "electrolyte_tolerance": "moderate", "pH_emulsion_stability_range": "5.0-9.5", "viscos…
ph_stability
{"optimal_ph_min": "5.0", "optimal_ph_max": "9.0", "stable_ph_min": "4.0", "stable_ph_max": "10.0", "degrades_above_ph": "11.0", "degrades_below_ph": "3.5", "ph_dependent_function": "Non-ionic; foam booster", "formulation_note": "Similar to DEA", "source": "Formulation literature"}
sensory
{"silky": "medium", "smooth, glides easily": "rich, thick foam", "dry-touch, non-greasy": "clean, soft", "instant": "moderate", "none": "very-high", "low": "high", "w/o": "o/w", "very-high": "moderate", "no": "no", "yes": "no", "1.40": "1.47", "transparent": "translucent", "colorless": "amber", "excellent": "good", "light": "medium", "synthetic": "botanical"}

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Emulsifier Foamant Softener and conditioner Surfactant (surface active agent) Thickening agent Viscosity modifier
Regulatory List Membership (1)
EU Restricted for Children (Cosmetics)

Expert Verdict

Expert safety assessment and concern-level summary for Cocamide MEA.

Regulatory Flags

eu_children_restricted

Known Synonyms

EINECS 268-770-2 UNII-C80684146D

Chemical Function

Surfactant (surface active agent) Viscosity modifier Softener and conditioner Emulsifier

Regulatory Lists

Europe; Personal care - body hygiene - hand soap children; Europe; Personal care children; Europe; Personal care - body hygiene - body wash children; Europe; Personal care - specialized bath products - bubble bath Europe; Personal care - hair styling and care - shampoo-dandruff Europe; Personal care - hair styling and care - shampoo-dandruff inert_ingredient; non_food_use; Pesticides

Australian Status

AICIS status: listed

Frequently Asked Questions

Is Cocamide MEA safe in cosmetics?

Cocamide MEA has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.

Is Cocamide MEA allowed in the EU?

Cocamide MEA EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Cocamide MEA do in cosmetics?

Cocamide MEA functions as: Surfactant. It is classified as a Surfactant in our database. CAS number: 68140-00-1.

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