Excellent Surfactant Sensitization Data

Lauryl Glucoside

Also known as: Dodecyl-beta-D-glucoside

INCI: LAURYL GLUCOSIDE

Lauryl Glucoside (CAS 59122-55-3) is a cosmetic surfactant functioning as Surfactant; cleanser; emulsifier; co-surfactant. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.

View industrial chemical safety profile for CAS 59122-55-3 →

Auto-generated CPSR Part A draft with source citations
Function
Surfactant; cleanser; emulsifier; co-surfactant
Safety Rating
EXCELLENT

Chemistry & Identifiers

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes CIR assessed alkyl glucosides as safe when formulated to be non-irritating. EWG rated 2. Longer C12-C16 chain length provides thicker, more stable foam vs decyl glucoside. Often paired with decyl glucoside for optimized foam-mildness balance in sulfate-free systems.

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Lauryl Glucoside.

Calculate MoS for your specific formulation with the MoS Calculator.

Sensitization Profile

Contact sensitization data for Lauryl Glucoside based on clinical patch test studies and IFRA standards.

Sensitization Rate
low
Allergen Class
surfactant
EU Allergen Listed
no
Patch Test Positive Rate
0.5%
Cross-reactivity Group
glucoside-group
Reaction Type
contact-dermatitis

Source: NACDG; IVDK; ESSCA

Typical Use Concentrations

Reported concentration ranges per product category from SCCS/CIR/industry sources.

Product Category Typical Range Max Reported Source
Shampoo 3–8 15 CIR/VCRP

Additional Ingredient Properties

10 property records from structured ingredient metadata.

acne
{"cas_number": "110615-47-9", "anti_acne_mechanism": "antibacterial", "comedogenicity_rating_0_to_5": "0-1", "acne_type_efficacy": "inflammatory", "sebum_reduction_pct_clinical": "0-5", "prescription_required_usa": "No", "otc_drug_monograph_category": "No", "max_otc_concentration_pct": "No limit", "japan_quasi_drug_anti_acne": "No", "korea_functional_cosmetic_acne": "No", "eu_cosmetic_restriction_…
allergen_detail
{"eu_allergen_listed": "no", "allergen_class": "surfactant", "cross_reactivity_group": "glucoside-group", "patch_test_frequency_pct": "0.5", "sensitization_rate": "low", "common_reaction_type": "contact-dermatitis", "ifra_restricted": "no", "source": "NACDG; IVDK; ESSCA"}
baby_pediatric
{"cas_number": "110615-47-9/59122-55-3", "ingredient_class": "cleanser_baby", "pediatric_safety_rating": "excellent", "minimum_age_months": "0", "neonatal_safe": "yes", "premature_infant_safe": "yes", "skin_barrier_maturity_consideration": "Glucose-derived, ultra-mild, biodegradable", "transepidermal_absorption_risk_pediatric": "low", "dose_per_kg_body_weight_concern": "Safe", "skin_surface_area_t…
comedogenicity_detail
{"comedogenicity_rating": "0", "irritancy_rating": "1", "skin_type_suitability": "all,oily,combination,normal,acne-prone", "acne_safe": "yes", "source": "Glucoside surfactant"}
concentration
{"min_concentration_pct": "5.0", "max_concentration_pct": "15.0", "typical_concentration_pct": "10.0", "product_type": "Body Wash", "function_at_concentration": "Gentle surfactant", "source": "CIR Safety Assessment"}
ecotoxicity
{"biodegradable": "yes", "biodegradation_days": "14-28", "bioaccumulative": "no", "aquatic_toxicity_level": "low", "coral_reef_safe": "yes", "marine_toxicity": "very low toxicity", "freshwater_toxicity": "minimal aquatic impact", "endocrine_disruptor": "no", "persistent_organic_pollutant": "no", "microplastic": "no", "nano_particle": "no", "hawaii_banned": "no", "eu_restricted_environmental": "no"…
emulsifier
{"cas_number": "110615-47-9", "ingredient_class": "O/W_emulsifier,liquid_crystal_former", "chemical_type": "alkyl_polyglucoside", "HLB_value": "13.0", "HLB_required_for_oil_phase": "12-14", "emulsion_type_primary": "O/W", "droplet_size_typical_um": "1-3", "critical_micelle_concentration_pct": "0.01-0.05", "surface_tension_reduction_mN_m": "32", "interfacial_tension_reduction": "36", "foam_formatio…
emulsion_hlb
{"hlb_value": "13.5", "hlb_required_as_emulsifier": "yes", "emulsifier_type": "o_w", "critical_packing_parameter": "0.23-0.35", "emulsion_stabilization_mechanism": "steric_stabilization", "co_emulsifier_pairs": "cetyl_alcohol,polyglyceryl_oleate", "optimal_oil_phase_pct": "5-15", "optimal_water_phase_pct": "85-95", "electrolyte_tolerance": "high", "pH_emulsion_stability_range": "3.0-9.0", "viscosi…

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Surfactant (surface active agent)
Regulatory List Membership (1)
EPA Safer Chemical Ingredients List (SCIL)

Expert Verdict

Expert safety assessment and concern-level summary for Lauryl Glucoside.

Regulatory Flags

apg nonionic ecocert cosmos biodegradable sulfate-free mild foam-optimized epa_safer_alternative

Known Synonyms

Dodecyl-beta-D-glucoside

Chemical Function

Surfactant (surface active agent)

Regulatory Lists

SCIL (9/2019)

Australian Status

AICIS status: listed

Cross-Vertical Safety Context

Same-CAS public records found in pharmaceutical data.

SOURCE ChEMBL / DrugCentral / FAERS DB_PHARMA CAS match

Pharmaceutical Data

Same-CAS rows from the pharmaceutical spoke database.

ChEMBL ID
CHEMBL4068837
View full pharmaceutical profile →

Frequently Asked Questions

Is Lauryl Glucoside safe in cosmetics?

Lauryl Glucoside has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.

Is Lauryl Glucoside allowed in the EU?

Lauryl Glucoside EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Lauryl Glucoside do in cosmetics?

Lauryl Glucoside functions as: Surfactant; cleanser; emulsifier; co-surfactant. It is classified as a Surfactant in our database. CAS number: 59122-55-3.

Is Lauryl Glucoside used outside cosmetics?

Lauryl Glucoside also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

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