Is Coco-Glucoside safe in cosmetics?
Coco-Glucoside has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Coco-Glucoside
Also known as: D-Glucopyranose, oligomeric, C10-16(even numbered) alkyl glycosides, EC 600-975-8, D-Glucopyranoside, oligomeric, alkyl (C10-16) glycosides, MIXTURE, D-GLUCOPYRASONE, OLIGOMERIC, C10-16-ALKYL GLYCOSIDES
INCI: COCO-GLUCOSIDE
Coco-Glucoside (CAS 110615-47-9) is a cosmetic surfactant functioning as Surfactant; cleanser; emulsifier; foam booster. NOAEL 100 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 110615-47-9 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Coco-Glucoside is classified GHS Danger (H315, H318) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Surfactant; cleanser; emulsifier; foam booster
Safety Rating
EXCELLENT
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
CIR assessed alkyl glucosides as safe when formulated to be non-irritating. EWG rated 2. ECOCERT/COSMOS certifiable. Longer chain length (C8–C16 coconut fraction) vs decyl glucoside provides denser, more stable foam.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Coco-Glucoside.
Calculate MoS for your specific formulation with the MoS Calculator.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for Coco-Glucoside across SCCS product categories, with measured dermal absorption where available.
Sensitization Profile
Contact sensitization data for Coco-Glucoside based on clinical patch test studies and IFRA standards.
Sensitization Rate
low
Allergen Class
surfactant
EU Allergen Listed
no
Patch Test Positive Rate
0.5%
Cross-reactivity Group
glucoside-group
Reaction Type
contact-dermatitis
Source: NACDG; IVDK; ESSCA
Dermal Penetration Profile
Skin absorption and penetration characteristics of Coco-Glucoside, relevant to systemic exposure and MoS calculations.
Absorption %
3-8%
Penetration Level
surface
Penetration Depth
stratum corneum
Molecular Weight
365.4 Da
Log P
1.5
Systemic Absorption
minimal
Topical Bioavailability
2-6%
Safety Margin Factor
low
Vehicle Dependent
Yes — absorption varies by formulation
Source: CIR
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10,000 - 100,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Typical Use Concentrations
Reported concentration ranges per product category from SCCS/CIR/industry sources.
| Product Category | Typical Range | Max Reported | Source |
|---|---|---|---|
| Shampoo | 3–8 | 15 | CIR/VCRP |
| Body Wash | 3–8 | 15 | CIR/VCRP |
Additional Ingredient Properties
10 property records from structured ingredient metadata.
allergen_detail
{"eu_allergen_listed": "no", "allergen_class": "surfactant", "cross_reactivity_group": "glucoside-group", "patch_test_frequency_pct": "0.5", "sensitization_rate": "low", "common_reaction_type": "contact-dermatitis", "ifra_restricted": "no", "source": "NACDG; IVDK; ESSCA"}
baby_pediatric
{"cas_number": "141464-42-8", "ingredient_class": "cleanser_baby", "pediatric_safety_rating": "excellent", "minimum_age_months": "0", "neonatal_safe": "yes", "premature_infant_safe": "yes", "skin_barrier_maturity_consideration": "Minimal penetration, naturally derived, pH-compatible", "transepidermal_absorption_risk_pediatric": "low", "dose_per_kg_body_weight_concern": "Safe at <15% use", "skin_su…
concentration
{"min_concentration_pct": "5.0", "max_concentration_pct": "15.0", "typical_concentration_pct": "10.0", "product_type": "Body Wash", "function_at_concentration": "Gentle surfactant", "source": "CIR Safety Assessment"}
dermal_absorption
{"molecular_weight_da": "365.4", "log_p_value": "1.5", "skin_penetration_level": "surface", "penetration_depth": "stratum corneum", "absorption_pct": "3-8", "systemic_absorption": "minimal", "penetration_enhancer": "yes", "occlusion_effect": "no", "vehicle_dependent": "yes", "skin_barrier_effect": "neutral", "bioavailability_topical_pct": "2-6", "safety_margin_factor": "low", "source": "CIR"}
emulsifier
{"cas_number": "68515-73-1", "ingredient_class": "O/W_emulsifier,liquid_crystal_former", "chemical_type": "alkyl_polyglucoside", "HLB_value": "11.5", "HLB_required_for_oil_phase": "11-13", "emulsion_type_primary": "O/W", "droplet_size_typical_um": "1-3", "critical_micelle_concentration_pct": "0.01-0.05", "surface_tension_reduction_mN_m": "31", "interfacial_tension_reduction": "35", "foam_formation…
hair_care
{"hair_function": "cleansing", "hair_type_suitability": "all", "curl_pattern_suitability": "all", "porosity_suitability": "all", "protein_sensitivity": "neutral", "moisture_protein_balance": "yes", "cg_method_approved": "not-a-silicone", "silicone_type": "not-a-sulfate", "sulfate_type": "no", "drying_alcohol": "no", "fatty_alcohol": "no", "heat_protectant": "yes", "color_safe": "neutral", "keratin…
pregnancy_detail
{"pregnancy_safe": "yes", "breastfeeding_safe": "yes", "risk_category": "not-rated", "reason": "Safe; gentle surfactant", "source": "COSMOS; dermatology literature"}
regulatory
{"eu_status": "allowed", "us_status": "allowed"}
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Cleaning agent
Emulsifier
Foamant
Surfactant (surface active agent)
Regulatory List Membership (2)
EU Regulated in Personal Care
EPA Safer Chemical Ingredients List (SCIL)
Expert Verdict
Expert safety assessment and concern-level summary for Coco-Glucoside.
Regulatory Flags
apg
nonionic
ecocert
cosmos
biodegradable
sulfate-free
mild
epa_safer_alternative
Known Synonyms
D-Glucopyranose, oligomeric, C10-16(even numbered) alkyl glycosides
EC 600-975-8
D-Glucopyranoside, oligomeric, alkyl (C10-16) glycosides
MIXTURE, D-GLUCOPYRASONE, OLIGOMERIC, C10-16-ALKYL GLYCOSIDES
Chemical Function
Surfactant (surface active agent)
Cleaning agent
Regulatory Lists
Europe; Vehicle - car interior
SCIL (9/2019)
inert_ingredient; non_food_use; Pesticides
Europe; Personal care
Europe; Personal care
Europe; Personal care
Europe; Personal care
Europe; Personal care
Europe; Personal care - body hygiene - hand soap
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Coco-Glucoside allowed in the EU?
Coco-Glucoside EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Coco-Glucoside do in cosmetics?
Coco-Glucoside functions as: Surfactant; cleanser; emulsifier; foam booster. It is classified as a Surfactant in our database. CAS number: 110615-47-9.
Is Coco-Glucoside used outside cosmetics?
Coco-Glucoside also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Coco-Glucoside have different safety status in cosmetics vs industrial chemicals?
Coco-Glucoside is classified GHS Danger (H315, H318) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check Coco-Glucoside compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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