Good Cosmetic Ingredient NOAEL Data

Calcium Benzoate

Also known as: Benzoic acid, calcium salt, EINECS 218-235-4, UNII-3QDE968MKD

INCI: CALCIUM BENZOATE

Calcium Benzoate (CAS 2090-05-3) is a cosmetic cosmetic ingredient functioning as Preservative. NOAEL 200 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: restricted, max 2.5%. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.

View industrial chemical safety profile for CAS 2090-05-3 →

Auto-generated CPSR Part A draft with source citations
Function
Preservative
Safety Rating
GOOD

Chemistry & Identifiers

EC Number
218-235-4

Regulatory Status

EU EU Status restricted
EU Max Conc. 2.5%
US US Status permitted
US Notes Adequate within Annex V limits

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Calcium Benzoate.

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Calcium Benzoate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL =300 mg/kg bw/day oral Rat short-term ToxValDB_ECHA_IUCLID

Pre-Calculated Safety Assessment

Pre-calculated NOAEL → SED → MoS audit trail for Calcium Benzoate across SCCS product categories, with measured dermal absorption where available.

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No

Additional Ingredient Properties

2 property records from structured ingredient metadata.

pediatric_safety
{"safe_for_newborn_0_6m": "yes", "safe_for_infant_6_12m": "yes", "safe_for_toddler_1_3y": "yes", "safe_for_child_3_12y": "yes", "safe_for_teen_12_18y": "yes", "pediatric_max_concentration_pct": "1.0", "adult_max_concentration_pct": "1.0", "pediatric_dermal_absorption_factor": "normal", "immature_skin_barrier_risk": "low", "oral_ingestion_risk": "low", "eye_irritation_risk": "low", "diaper_area_saf…
preservative
{"preservative_class": "Organic acid", "antimicrobial_spectrum_bacteria_gp": "Good", "antimicrobial_spectrum_bacteria_gn": "Moderate", "antimicrobial_spectrum_yeast": "Moderate", "antimicrobial_spectrum_mold": "Yes", "mic_staph_aureus_ppm": "140", "mic_e_coli_ppm": "200", "mic_pseudomonas_ppm": "260", "mic_candida_albicans_ppm": "550", "mic_aspergillus_niger_ppm": "950", "challenge_test_pass_conce…

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Biocide Preservative
Regulatory List Membership (1)
FDA Substances Added to Food (EAFUS)

Expert Verdict

Expert safety assessment and concern-level summary for Calcium Benzoate.

Regulatory Flags

preservative fda_food_additive

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to Calcium Benzoate by CAS number or substance name.

Studies
1
Lowest NOAEL
300 mg/kg bw/day
Highest NOAEL
300 mg/kg bw/day
ToxValDB_ECHA_IUCLID

Known Synonyms

Benzoic acid, calcium salt EINECS 218-235-4 UNII-3QDE968MKD

Chemical Function

Preservative Biocide

Regulatory Lists

inert_ingredient; Pesticides inert_ingredient; non_food_use; Pesticides inert_ingredient; non_food_use; Pesticides inert_ingredient; non_food_use; Pesticides active_ingredient; animal_products; Europe; pharmaceutical; residue food_additive; Substances Added to Food (formerly EAFUS) (2/2019)

Australian Status

AICIS status: listed

Frequently Asked Questions

Is Calcium Benzoate safe in cosmetics?

Calcium Benzoate has a safety rating of "GOOD" in our database. EU status: restricted. US status: permitted. 1 toxicological study endpoint(s) are available in our database.

Is Calcium Benzoate allowed in the EU?

Calcium Benzoate EU regulatory status: restricted. Maximum allowed concentration: 2.5%. This is based on EU Regulation 1223/2009 and its amendments.

What does Calcium Benzoate do in cosmetics?

Calcium Benzoate functions as: Preservative. It is classified as a cosmetic ingredient in our database. CAS number: 2090-05-3.

What is the NOAEL for Calcium Benzoate?

The NOAEL (No Observed Adverse Effect Level) for Calcium Benzoate is =300 mg/kg bw/day based on a short-term study via oral route in Rat. Source: ToxValDB_ECHA_IUCLID.

Is Calcium Benzoate used outside cosmetics?

Calcium Benzoate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

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