What is the NOAEL for Calcium dibenzoate?
Calcium dibenzoate has 14 NOAEL studies in the database. The lowest reported value is 5 mg/kg via oral in Human. Source: ToxValDB_WHO_JECFA_ADI.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Calcium dibenzoate
Also known as: Benzoic acid, calcium salt, Calcium benzoate, EINECS 218-235-4, UNII-3QDE968MKD
CAS 2090-05-3
Calcium dibenzoate (CAS 2090-05-3) is a chemical substance. Key regulatory status: REACH registered, 6 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
14
SOURCE
chemical inventory jurisdictions
Regulatory lists
6
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
10 fields
Name
Calcium dibenzoate
CAS Number
2090-05-3
DTXSID
DTXSID4044612
Molecular Formula
2C7H6O2.Ca
InChI Key
NSQPPSOSXWOZNH-UHFFFAOYSA-L
Monoisotopic Mass
284.03615
Synonyms
Benzoic acid, calcium saltCalcium benzoateEINECS 218-235-4UNII-3QDE968MKD
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
2 records
PreservativeBiocide
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
6 records
| List | Keyword | Source |
|---|---|---|
| inert_ingredient; Pesticides | EPA | CPCat |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| active_ingredient; animal_products; Europe; pharmaceutical; residue | EU | CPCat |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 14 of 14 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| <=5 | mg/kg | ADI | oral | Human | ToxValDB_WHO_JECFA_ADI |
| =5 | mg/kg bw/day | ADI (group) | - | Consumers | EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx |
| =5 | mg/kg bw/day | ADI (group) | - | Consumers | EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx |
| 3QDE968MKD | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3QDE968MKD | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3QDE968MKD | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3QDE968MKD | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =300 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =500 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_EFSA |
| =500 | mg/kg bw/day | NOAEL | oral: feed | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| =500 | mg/kg bw/day | NOAEL | oral: feed | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| =1310 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_EFSA |
| =1310 | mg/kg bw/day | NOAEL | oral: feed | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| =1310 | mg/kg bw/day | NOAEL | oral: feed | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
Showing 14 of 14 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Calcium dibenzoate | 218-235-4 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
2.5%
Category
Preservative
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
E213 — ADI: 5 mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Calcium dibenzoate?
Calcium dibenzoate appears on 4 regulatory/inventory lists including inert_ingredient; Pesticides, inert_ingredient; non_food_use; Pesticides, active_ingredient; animal_products; Europe; pharmaceutical; residue, and 1 more. Source: EPA CPDat.
Is Calcium dibenzoate used in cosmetics?
Yes, Calcium dibenzoate is also indexed as a cosmetic ingredient under the name Calcium Benzoate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Calcium dibenzoate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Calcium dibenzoate used outside industrial chemicals?
Calcium dibenzoate also appears in cosmetics, food safety, cannabis databases.