Also known as: E-Z Preparations, Artificial barite, Artificial heavy spar, Baraflave, Baricon (+15 more)
INCI: BARIUM SULFATE
Barium Sulfate (CAS 7727-43-7) is a cosmetic cosmetic ingredient functioning as Colorant (white pigment), Opacifying agent. Reported NOAEL =179.5 mg/kg bw/day in Rat (ToxValDB_ECHA_IUCLID); EU Regulation 1223/2009 status: permitted; 1 safety opinion reviewed (cir). Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
US NotesFDA delisted barium sulfate as a color additive and it is no longer authorized under color additive regulations (21 CFR Part 82). If used in US cosmetics, should be positioned under opacifying agent function rather than as a color additive to avoid regulatory conflict. CIR Final Report (June 2014, published IJT 2018) assessed it as safe at current use concentrations with the condition that formulation must be non-irritating.
For full compliance data across multiple jurisdictions, use the
Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Barium Sulfate.
Calculate MoS for your specific formulation with the
MoS Calculator.
Toxicological Studies
2 study endpoints found for Barium Sulfate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
Endpoint
Value
Route
Species
Study Type
Source
NOAEL
=179.5 mg/kg bw/day
oral
Rat
reproduction developmental
ToxValDB_ECHA_IUCLID
NOAEL
=201.5 mg/kg bw/day
oral
Rat
reproduction developmental
ToxValDB_ECHA_IUCLID
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Long-term Exposure Effects
Repeated or prolonged inhalation of dust particles may cause effects on the lungs. This may result in baritosis (a form of benign pneumoconiosis).
Routes of Exposure
The substance can be absorbed into the body by inhalation of its aerosol.
Safety Opinions
Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).
cir
Verdict: safe
lfate should be formulated to be non- irritating. The Panel concluded that barium sulfate is safe in cosmetics in the present practices of use and concentration described in this safety assessment when formulated to be nonirritating. Keywords barium sulfate, safety, cosmetics Introduction The saf
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10,000 - 100,000 tonnes
Substance Type
GROUP; SUBSTANCE
SVHC Candidate
No
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex IV — Permitted Colorants
Product type: White
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (IV - Colorants)
BRIN Brazil/India Cosmetics
India: Permitted Colorant
Additional Jurisdictional Restrictions (2)
Jurisdiction
Status
Max %
Product Type
BR
permitted_colorant
-
Column 1: All products
ASEAN
permitted_colorant
-
All products
Additional Ingredient Properties
1 property record from structured ingredient metadata.
E-Z PreparationsArtificial bariteArtificial heavy sparBaraflaveBariconBarii sulphasBaritop 100Baritop G PowderBarium AndreuBarium sulfuricumBarobagBarocatBarodenseBaroloidBarosperse 110Barosperse IIBar-TestBarytesBarytgenBaryx Colloidal
Chemical Function
DyeOpaciferPigmentFiller
Regulatory Lists
inert_ingredient; non_food_use; PesticidesIndirect additives food contact (10/2018)Europe; plastic_additiveEurope; Personal careCanada; pharmaceuticalinert_ingredient; PesticidesArts and crafts/Office supplies - general arts and crafts supplies - arts and crafts paint; Europedrinking_water; Europe; manufacturing; plastic_additive
Australian Status
AICIS status:listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCEChEMBL / DrugCentral / FAERSDB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Barium Sulfate has a safety rating of "GOOD" in our database. EU status: permitted. US status: restricted. 2 toxicological study endpoint(s) are available in our database. This ingredient has been reviewed by cir.
Is Barium Sulfate allowed in the EU?
Barium Sulfate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Barium Sulfate do in cosmetics?
Barium Sulfate functions as: Colorant (white pigment), Opacifying agent. It is classified as a cosmetic ingredient in our database. CAS number: 7727-43-7.
What is the NOAEL for Barium Sulfate?
The NOAEL (No Observed Adverse Effect Level) for Barium Sulfate is =179.5 mg/kg bw/day based on a reproduction developmental study via oral route in Rat. A total of 2 study endpoints are available. Source: ToxValDB_ECHA_IUCLID.
Is Barium Sulfate used outside cosmetics?
Barium Sulfate also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Barium Sulfate have different safety status in cosmetics vs industrial chemicals?
Barium Sulfate is classified GHS Danger (H302, H332, H372, H402, H412) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check Barium Sulfate compliance across multiple jurisdictions:
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.