Is Acid Orange 6 safe in cosmetics?
Acid Orange 6 has a safety rating of "POOR" in our database. EU status: prohibited. US status: prohibited.
Poor
Cosmetic Ingredient
Acid Orange 6
Also known as: 2,4-Dihydroxyazobenzene-4′-sulfonate sodium salt, Benzenesulfonic acid, 4-[2-(2,4-dihydroxyphenyl)diazenyl]-, sodium salt (1:1), Acid Leather Yellow PGW, Acid Phosphine G New, Acme Yellow Acid Yellow RS (+14 more)
INCI: ACID ORANGE 6
Acid Orange 6 (CAS 547-57-9) is a cosmetic cosmetic ingredient functioning as Colorant (primarily a laboratory pH indicator). EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 547-57-9 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Acid Orange 6 is prohibited in EU cosmetics but has active industrial GHS classifications.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word
Function
Colorant (primarily a laboratory pH indicator)
Safety Rating
POOR
Chemistry & Identifiers
IUPAC Name
sodium 4-[(2,4-dihydroxyphenyl)diazenyl]benzenesulfonate
InChIKey
COEZWFYORILMOM-UHFFFAOYSA-M
Regulatory Status
EU EU Status
prohibited
US US Status
prohibited
US Notes
Not FDA-approved for cosmetic use
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Acid Orange 6.
Calculate MoS for your specific formulation with the MoS Calculator.
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex IV — Permitted Colorants
Product type: Orange
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (IV - Colorants)
BRIN Brazil/India Cosmetics
India: Permitted Colorant
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (1)
JECFA Evaluation
CI FOOD YELLOW 8 | 1977 | DECISION POSTPONED | TRS 617-JECFA 21/18 | FAS 12-JECFA 21/72
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Dye
Regulatory List Membership (2)
EU Regulated in Personal Care
EU CosIng Cosmetics Ingredient Database
Expert Verdict
Expert safety assessment and concern-level summary for Acid Orange 6.
Regulatory Flags
colorant
eu_cosing_listed
Known Synonyms
2,4-Dihydroxyazobenzene-4′-sulfonate sodium salt
Benzenesulfonic acid, 4-[2-(2,4-dihydroxyphenyl)diazenyl]-, sodium salt (1:1)
Acid Leather Yellow PGW
Acid Phosphine G New
Acme Yellow Acid Yellow RS
Benzenesulfonic acid, 4-[(2,4-dihydroxyphenyl)azo]-, monosodium salt
Benzenesulfonic acid, p-(2,4-dihydroxyphenylazo)-, sodium salt
C Yellow 12
C.I. 14270
C.I. Acid Orange 6, monosodium salt
C.I. Food Yellow 8
Cetil Chromine Yellow GR
Chrysoin
Chrysoin G
Chrysoin S
Chrysoin S Specially Pure
Chrysoine
Chrysoine Extra
Chrysoine Extra Pure A
Chemical Function
Dye
Regulatory Lists
Europe; Personal care
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Acid Orange 6 allowed in the EU?
Acid Orange 6 EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Acid Orange 6 do in cosmetics?
Acid Orange 6 functions as: Colorant (primarily a laboratory pH indicator). It is classified as a cosmetic ingredient in our database. CAS number: 547-57-9.
Is Acid Orange 6 used outside cosmetics?
Acid Orange 6 also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Acid Orange 6 have different safety status in cosmetics vs industrial chemicals?
Acid Orange 6 is prohibited in EU cosmetics but has active industrial GHS classifications.
Compliance Tools
Check Acid Orange 6 compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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