Is Sparteine safe in cosmetics?
Sparteine has a safety rating of "POOR" in our database. EU status: prohibited. US status: prohibited.
Poor
Cosmetic Ingredient
Sparteine
Also known as: 7,14-Methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocine, dodecahydro-, (7S,7aR,14S,14aS)-, L-Sparteine, (7S,7aR,14S,14aS)-Dodecahydro-7,14-methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocine, L-(-)-Sparteine
INCI: SPARTEINE
Sparteine (CAS 90-39-1) is a cosmetic cosmetic ingredient functioning as Pharmacologically active alkaloid. EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 90-39-1 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Sparteine is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H312, H332).
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Pharmacologically active alkaloid
Safety Rating
POOR
Chemistry & Identifiers
IUPAC Name
(1S,2R,9S,10S)-7,15-diazatetracyclo[7.7.1.02,7.010,15]heptadecane
InChIKey
SLRCCWJSBJZJBV-ZQDZILKHSA-N
Regulatory Status
EU EU Status
prohibited
US US Status
prohibited
US Notes
Not explicitly listed on FDA prohibited list, but classified as a drug substance; use in cosmetics would likely trigger drug classification
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Sparteine.
Calculate MoS for your specific formulation with the MoS Calculator.
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex II — Prohibited
Ref: 299
(EC) 2009/1223
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (II - Prohibited)
BRIN Brazil/India Cosmetics
Brazil: Prohibited
India: Prohibited (GNRAS)
Additional Jurisdictional Restrictions (3)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| IN | banned | - | all cosmetics |
| CA | banned | - | - |
| KR | prohibited | - | - |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Fragrance
Regulatory List Membership (2)
EU Banned in Cosmetics
EU CosIng Cosmetics Ingredient Database
Expert Verdict
Expert safety assessment and concern-level summary for Sparteine.
Regulatory Flags
eu_banned_cosmetics
eu_cosing_listed
Known Synonyms
7,14-Methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocine, dodecahydro-, (7S,7aR,14S,14aS)-
L-Sparteine
(7S,7aR,14S,14aS)-Dodecahydro-7,14-methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocine
L-(-)-Sparteine
Chemical Function
Fragrance
Regulatory Lists
Canada; consumer_product; Substances in Products - Canada (4/2014)
pharmaceutical
Canada; pharmaceutical
banned; Europe; Personal care
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
SPARTEINE
ChEMBL ID
CHEMBL1908847
Max Phase
4
Frequently Asked Questions
Is Sparteine allowed in the EU?
Sparteine EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Sparteine do in cosmetics?
Sparteine functions as: Pharmacologically active alkaloid. It is classified as a cosmetic ingredient in our database. CAS number: 90-39-1.
Is Sparteine used outside cosmetics?
Sparteine also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Sparteine have different safety status in cosmetics vs industrial chemicals?
Sparteine is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H312, H332).
Compliance Tools
Check Sparteine compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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