What is the NOAEL for Sparteine?
Sparteine has 5 NOAEL studies in the database. The lowest reported value is 298897D62S UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Sparteine
Also known as: 7,14-Methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocine, dodecahydro-, (7S,7aR,14S,14aS)-, L-Sparteine, (7S,7aR,14S,14aS)-Dodecahydro-7,14-methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocine, L-(-)-Sparteine
CAS 90-39-1
Sparteine (CAS 90-39-1) is a chemical substance. Key regulatory status: 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.
Cross-Vertical Regulatory Divergence
Sparteine is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H312, H332).
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
5
SOURCE
chemical inventory jurisdictions
Regulatory lists
4
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
10 fields
Name
Sparteine
CAS Number
90-39-1
DTXSID
DTXSID4023591
Molecular Formula
C15H26N2
InChI Key
SLRCCWJSBJZJBV-ZQDZILKHSA-N
Monoisotopic Mass
234.209599
Synonyms
7,14-Methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocine, dodecahydro-, (7S,7aR,14S,14aS)-L-Sparteine(7S,7aR,14S,14aS)-Dodecahydro-7,14-methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocineL-(-)-Sparteine
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
1 records
Fragrance
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| Canada; consumer_product; Substances in Products - Canada (4/2014) | Government of Canada | CPCat |
| pharmaceutical | US International Trade Commission | CPCat |
| Canada; pharmaceutical | DrugBank | DrugBank |
| banned; Europe; Personal care | European Commission | CosIng |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 5 of 5 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 298897D62S | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 298897D62S | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 298897D62S | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 298897D62S | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =960 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
Showing 5 of 5 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Cosmetic Ingredient
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
SPARTEINE
ChEMBL Phase
4
Adverse Events
0
Bioactivity
4
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Sparteine?
Sparteine appears on 4 regulatory/inventory lists including Canada; consumer_product; Substances in Products - Canada (4/2014), pharmaceutical, Canada; pharmaceutical, and 1 more. Source: EPA CPDat.
Is Sparteine used in cosmetics?
Yes, Sparteine is also indexed as a cosmetic ingredient under the name Sparteine. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Sparteine come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Does Sparteine have different safety status in cosmetics vs industrial chemicals?
Sparteine is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H312, H332).
Is Sparteine used outside industrial chemicals?
Sparteine also appears in cosmetics, pharmaceutical, cannabis databases.