PVP

Also known as: K 115, Agrimer, Caswell No. 681, EPA Pesticide Chemical Code 079033, 1-Ethenyl-2-pyrrolidinone polymers (+15 more)

PVP (CAS 9003-39-8) is a cosmetic cosmetic ingredient functioning as film-forming, adhesion promoter, hair-fixative. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.

View industrial chemical safety profile for CAS 9003-39-8 →

Auto-generated CPSR Part A draft with source citations
Function
film-forming, adhesion promoter, hair-fixative
Safety Rating
EXCELLENT

Chemistry & Identifiers

EC Number
618-373-9

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes Permitted as inactive ingredient in cosmetics without restriction. GRAS as food additive under 21 CFR 172.210 and 173.55. Not a sunscreen active ingredient.

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for PVP.

Calculate MoS for your specific formulation with the MoS Calculator.

EPA ToxValDB — Toxicity Values

5 toxicity values from EPA ToxValDB (aggregated from CCTE, HPV, ToxRefDB, IRIS, and other regulatory dossiers).

Endpoint Value Species Route Duration Source
ADI <=50 mg/kg Human oral - WHO JECFA ADI
LD50 =100000 mg/kg Guinea Pig oral - ChemIDplus
LD50 >40000 mg/kg Mouse oral - ChemIDplus
LD50 =1040 mg/kg Rabbit oral - ChemIDplus
LD50 =100000 mg/kg Rat oral - ChemIDplus

IARC Carcinogenicity

International Agency for Research on Cancer (WHO) monograph evaluation.

IARC Group
3
Volume
19, Sup 7, 71
Evaluation Year
1998

Typical Use Concentrations

Reported concentration ranges per product category from SCCS/CIR/industry sources.

Product Category Typical Range Max Reported Source
Hair Spray 5–10 15 CIR/VCRP
Sunscreen 0.5–2 5 CIR/VCRP

Additional Ingredient Properties

4 property records from structured ingredient metadata.

baby_pediatric
{"cas_number": "9003-39-8", "ingredient_class": "other", "pediatric_safety_rating": "good", "minimum_age_months": "0", "neonatal_safe": "yes", "premature_infant_safe": "yes", "skin_barrier_maturity_consideration": "Polyvinylpyrrolidone, film former", "transepidermal_absorption_risk_pediatric": "very_low", "dose_per_kg_body_weight_concern": "Polymer non-absorbed", "skin_surface_area_to_weight_ratio…
hair_care
{"hair_function": "styling", "hair_type_suitability": "all", "curl_pattern_suitability": "all", "porosity_suitability": "all", "protein_sensitivity": "neutral", "moisture_protein_balance": "yes", "cg_method_approved": "not-a-silicone", "silicone_type": "not-a-sulfate", "sulfate_type": "no", "drying_alcohol": "no", "fatty_alcohol": "no", "heat_protectant": "yes", "color_safe": "neutral", "keratin_b…
polymer
{"cas_number": "9003-39-8", "ingredient_class": "film_former/hair_fixative", "polymer_type": "synthetic_homopolymer", "chemical_backbone": "vinyl_pyrrolidone", "molecular_weight_Da_range": "10000-1500000", "molecular_weight_distribution_PDI": "2.0-3.5", "glass_transition_temp_Tg_C": "175-180", "crystallinity_pct": "0", "branching_degree": "low", "ionic_character": "nonionic", "charge_density_meq_g…
regulatory
{"eu_status": "allowed", "us_status": "allowed"}

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Anti-static agent Binder Dispersing agent Emulsifier Film former Fixing agent (mordant) Fragrance Hair fixative Pharmaceutical excipient Processing aids not otherwise specified
Regulatory List Membership (4)
EU Restricted for Children (Cosmetics) IFRA Fragrance Transparency List EPA Safer Chemical Ingredients List (SCIL) FDA Substances Added to Food (EAFUS)

Expert Verdict

Expert safety assessment and concern-level summary for PVP.

Regulatory Flags

eu-unrestricted cir-approved gras-fda no-sccs-opinion eu_children_restricted epa_safer_alternative ifra_fragrance fda_food_additive

Known Synonyms

K 115 Agrimer Caswell No. 681 EPA Pesticide Chemical Code 079033 1-Ethenyl-2-pyrrolidinone polymers Ganex p-804 Luviskol Luviskol K30 Luviskol K90 NCI-C60582 NSC 114022 NSC 142693 Peragal ST Periston-N Plasdone K-26/28 Plasdone No. 4 Polyclar A. T. Polyclar-AT Poly(1-ethenyl-2-pyrrolidinone) Polygyl

Chemical Function

Film former Anti-static agent Viscosity modifier Emulsifier Hair fixative Binder Fixing agent (mordant)

Regulatory Lists

IFRA Transparency Canada; consumer_product; Substances in Products - Canada (4/2014) inert_ingredient; non_food_use; Pesticides active_ingredient; Australia pharmaceutical Europe; Personal care - oral and dental care - teeth whitener drinking_water; Europe; manufacturing; plastic_additive inert_ingredient; Pesticides CEDI food_additive; Substances Added to Food (formerly EAFUS) (2/2019) SCIL (9/2019) Cleaning products and household care - laundry and fabric treatment - laundry detergent; Europe Europe; Personal care - oral and dental care - teeth whitener Europe; Personal care - oral and dental care - teeth whitener pharmaceutical Canada; pharmaceutical Europe; Personal care - oral and dental care - teeth whitener children; Europe; Personal care

Australian Status

AICIS status: listed

Cross-Vertical Safety Context

Same-CAS public records found in pharmaceutical data.

SOURCE ChEMBL / DrugCentral / FAERS DB_PHARMA CAS match

Pharmaceutical Data

Same-CAS rows from the pharmaceutical spoke database.

Compound
crospovidone
ChEMBL ID
CHEMBL2108139
Adverse Event Associations
89
View full pharmaceutical profile →

Frequently Asked Questions

Is PVP safe in cosmetics?

PVP has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.

Is PVP allowed in the EU?

PVP EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does PVP do in cosmetics?

PVP functions as: film-forming, adhesion promoter, hair-fixative. It is classified as a cosmetic ingredient in our database. CAS number: 9003-39-8.

Is PVP used outside cosmetics?

PVP also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

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