Good Cosmetic Ingredient Dermal Penetration

Dimethiconol

INCI: DIMETHICONOL

Dimethiconol (CAS 70131-67-8) is a cosmetic cosmetic ingredient functioning as film-forming, hair conditioning, emollient, long-wear binder. EU Regulation 1223/2009 status: permitted.

CAS Number
70131-67-8
Function
film-forming, hair conditioning, emollient, long-wear binder
Safety Rating
GOOD

Chemistry & Identifiers

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes No FDA restriction; high-MW silicone gum considered safe at cosmetic use levels; not separately restricted

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Dimethiconol - available to Pro subscribers.

Calculate MoS for your specific formulation with the MoS Calculator.

Dermal Penetration Profile

Skin absorption and penetration characteristics of Dimethiconol, relevant to systemic exposure and MoS calculations.

Absorption %
0.1-0.3%
Penetration Level
surface
Penetration Depth
surface only
Molecular Weight
Variable Da
Log P
6.5
Systemic Absorption
minimal
Topical Bioavailability
0.05-0.1%
Safety Margin Factor
minimal

Source: CIR

Additional Ingredient Properties

10 property records from structured ingredient metadata.

acne
{"cas_number": "31692-79-2", "anti_acne_mechanism": "anti_inflammatory", "comedogenicity_rating_0_to_5": "1", "acne_type_efficacy": "inflammatory", "sebum_reduction_pct_clinical": "0-5", "prescription_required_usa": "No", "otc_drug_monograph_category": "No", "max_otc_concentration_pct": "No limit", "japan_quasi_drug_anti_acne": "No", "korea_functional_cosmetic_acne": "No", "eu_cosmetic_restriction…
anti_pollution
{"cas_number": "31692-79-2", "ingredient_class": "anti_pollution", "primary_mechanism": "film_forming_barrier", "pollution_types_targeted": "PM2_5", "IR_A_protection": "no", "visible_light_protection": "no", "digital_screen_protection_claim": "no", "PAH_neutralization": "no", "ozone_protection": "no", "mitochondrial_protection": "no", "Nrf2_activation": "no", "AhR_pathway_modulation": "no", "NF_kB…
baby_pediatric
{"cas_number": "31692-79-2", "ingredient_class": "other", "pediatric_safety_rating": "excellent", "minimum_age_months": "0", "neonatal_safe": "yes", "premature_infant_safe": "yes", "skin_barrier_maturity_consideration": "Film-forming silicone", "transepidermal_absorption_risk_pediatric": "very_low", "dose_per_kg_body_weight_concern": "Non-absorbed polymer", "skin_surface_area_to_weight_ratio_relev…
comedogenicity_detail
{"comedogenicity_rating": "1", "irritancy_rating": "0", "skin_type_suitability": "all,dry,combination,normal", "acne_safe": "yes", "source": "High MW silicone"}
concentration
{"min_concentration_pct": "0.5", "max_concentration_pct": "3.0", "typical_concentration_pct": "1.5", "product_type": "Hair Conditioner", "function_at_concentration": "Conditioning, shine", "source": "CIR Safety Assessment"}
dermal_absorption
{"molecular_weight_da": "Variable", "log_p_value": "6.5", "skin_penetration_level": "surface", "penetration_depth": "surface only", "absorption_pct": "0.1-0.3", "systemic_absorption": "minimal", "penetration_enhancer": "no", "occlusion_effect": "yes", "vehicle_dependent": "no", "skin_barrier_effect": "neutral", "bioavailability_topical_pct": "0.05-0.1", "safety_margin_factor": "minimal", "source":…
ecotoxicity
{"biodegradable": "no", "biodegradation_days": "1200+", "bioaccumulative": "yes", "aquatic_toxicity_level": "low", "coral_reef_safe": "unknown", "marine_toxicity": "very low toxicity", "freshwater_toxicity": "persistent", "soil_toxicity": "sediment accumulation", "endocrine_disruptor": "no", "persistent_organic_pollutant": "yes", "microplastic": "no", "nano_particle": "no", "hawaii_banned": "no", …
emulsion_hlb
{"hlb_required_as_emulsifier": "no", "emulsifier_type": "w_o", "emulsion_stabilization_mechanism": "steric_stabilization", "co_emulsifier_pairs": "cetyl_dimethicone_copolyol", "optimal_oil_phase_pct": "50-85", "optimal_water_phase_pct": "15-50", "droplet_size_range_um": "1-25", "creaming_resistance": "moderate", "coalescence_resistance": "good", "ostwald_ripening_resistance": "good", "freeze_thaw_…

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Binder Defoamer Dispersing agent Flow promoter Sealant (barrier) Surface modifier Viscosity modifier Waterproofing agent Wetting agent (non-aqueous)
Regulatory List Membership (1)
EPA Safer Chemical Ingredients List (SCIL)

Expert Verdict

Expert safety assessment and concern-level summary for Dimethiconol - available to Pro subscribers.

Regulatory Flags

non-volatile-silicone high-molecular-weight film-former long-wear hair-conditioning cosmos-prohibited epa_safer_alternative

Frequently Asked Questions

Is Dimethiconol safe in cosmetics?

High-MW silicone gum with terminal hydroxyl groups providing robust film-forming for hair conditioning and long-wear color cosmetics. Superior film cohesion vs. standard dimethicone fluids due to gum-like consistency. Not subject to EU cyclic siloxane restrictions. Widely used in professional hair care for frizz control, split-end sealing, and thermal protection. The EU classifies Dimethiconol as "permitted". Safety rating: GOOD.

Is Dimethiconol allowed in the EU?

Dimethiconol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Dimethiconol do in cosmetics?

Dimethiconol functions as: film-forming, hair conditioning, emollient, long-wear binder. It is classified as a cosmetic ingredient in our database. CAS number: 70131-67-8.

What is the Margin of Safety for Dimethiconol?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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