Good Cosmetic Ingredient Dermal Penetration

Acrylates Copolymer

INCI: ACRYLATES COPOLYMER

Acrylates Copolymer (CAS 25212-95-3) is a cosmetic cosmetic ingredient functioning as film-forming, adhesion promoter, long-wear agent. EU Regulation 1223/2009 status: permitted.

CAS Number
25212-95-3
Function
film-forming, adhesion promoter, long-wear agent
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes CIR assessed acrylate/methacrylate copolymers as safe in cosmetics when formulated to be non-irritating. Residual unreacted acrylic acid/acrylate monomers must be controlled below irritant threshold. Provides adhesion and transfer resistance in lip products.

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Acrylates Copolymer - available to Pro subscribers.

Calculate MoS for your specific formulation with the MoS Calculator.

Dermal Penetration Profile

Skin absorption and penetration characteristics of Acrylates Copolymer, relevant to systemic exposure and MoS calculations.

Absorption %
0%
Penetration Level
surface
Penetration Depth
surface only
Molecular Weight
Variable Da
Log P
n/a
Systemic Absorption
no
Topical Bioavailability
0%
Safety Margin Factor
none

Source: CIR

Additional Ingredient Properties

10 property records from structured ingredient metadata.

anti_pollution
{"cas_number": "9003-01-4", "ingredient_class": "anti_pollution", "primary_mechanism": "film_forming_barrier", "pollution_types_targeted": "PM2_5", "IR_A_protection": "no", "visible_light_protection": "no", "digital_screen_protection_claim": "no", "PAH_neutralization": "no", "ozone_protection": "no", "mitochondrial_protection": "no", "Nrf2_activation": "no", "AhR_pathway_modulation": "no", "NF_kB_…
baby_pediatric
{"cas_number": "9003-01-4", "ingredient_class": "other", "pediatric_safety_rating": "good", "minimum_age_months": "3", "neonatal_safe": "no", "premature_infant_safe": "insufficient_data", "skin_barrier_maturity_consideration": "Film former, versatile", "transepidermal_absorption_risk_pediatric": "very_low", "dose_per_kg_body_weight_concern": "Polymer non-absorbed", "skin_surface_area_to_weight_rat…
comedogenicity_detail
{"comedogenicity_rating": "0", "irritancy_rating": "1", "skin_type_suitability": "all,oily,combination,normal", "acne_safe": "yes", "source": "Film former"}
concentration
{"min_concentration_pct": "1.0", "max_concentration_pct": "8.0", "typical_concentration_pct": "4.0", "product_type": "Hair Spray", "function_at_concentration": "Hold agent", "source": "CIR Safety Assessment"}
cost_pricing
{"cost_tier": "budget", "estimated_cost_per_kg_usd_low": "15", "estimated_cost_per_kg_usd_high": "28", "natural_premium_markup_pct": "0", "organic_certified_premium_pct": "0", "supply_chain_volatility": "low", "primary_source_region": "Global", "bulk_discount_threshold_kg": "150", "seasonal_price_variation": "low", "commodity_or_specialty": "commodity", "substitute_ingredients": "VP/VA Copolymer, …
deodorant
{"cas_number": "25133-97-5", "ingredient_class": "other", "mechanism_of_action": "other", "antiperspirant_efficacy_sweat_reduction_pct": "0", "deodorant_efficacy_hours": "0", "odor_reduction_pct": "0", "bacteriostatic": "no", "bactericidal": "no", "microbiome_impact": "neutral", "axillary_microbiome_effect": "varies by ingredient", "MIC_value_if_antimicrobial": "varies", "astringency_level": "vari…
dermal_absorption
{"molecular_weight_da": "Variable", "skin_penetration_level": "surface", "penetration_depth": "surface only", "absorption_pct": "0", "systemic_absorption": "no", "penetration_enhancer": "no", "occlusion_effect": "no", "vehicle_dependent": "no", "skin_barrier_effect": "neutral", "bioavailability_topical_pct": "0", "source": "CIR"}
ecotoxicity
{"biodegradable": "no", "biodegradation_days": "non-biodegradable", "bioaccumulative": "no", "aquatic_toxicity_level": "low", "coral_reef_safe": "unknown", "marine_toxicity": "physical harm", "freshwater_toxicity": "ingestion", "soil_toxicity": "persistent", "endocrine_disruptor": "no", "persistent_organic_pollutant": "no", "microplastic": "yes", "nano_particle": "no", "hawaii_banned": "no", "eu_r…

Expert Verdict

Expert safety assessment and concern-level summary for Acrylates Copolymer - available to Pro subscribers.

Regulatory Flags

cir-approved film-former long-wear transfer-resistant residual-monomer-caution quality-control-critical oral-exposure-relevant adhesion-agent matte-lipstick

Frequently Asked Questions

Is Acrylates Copolymer safe in cosmetics?

Acrylate copolymer film former providing adhesion and transfer resistance in long-wear lip products. CIR confirms safety when residual monomer content is controlled—unreacted acrylate monomers are the critical safety variable. No regulatory restrictions. Specify maximum residual monomer concentration in supplier specifications. The EU classifies Acrylates Copolymer as "permitted". Safety rating: GOOD.

Is Acrylates Copolymer allowed in the EU?

Acrylates Copolymer EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Acrylates Copolymer do in cosmetics?

Acrylates Copolymer functions as: film-forming, adhesion promoter, long-wear agent. It is classified as a cosmetic ingredient in our database. CAS number: 25212-95-3.

What is the Margin of Safety for Acrylates Copolymer?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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