Is Polyquaternium-28 safe in cosmetics?
Polyquaternium-28 has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Polyquaternium-28
Also known as: 2-Methyl-N-[3-(trimethylazaniumyl)propyl]prop-2-enimidate--1-ethenylpyrrolidin-2-one--hydrogen chloride (1/1/1), Gafquat HS-100, N,N,N-Trimethyl-3-((2-methyl-1-oxo-2-propenyl)amino)-1-propanaminium chloride, Copolymer of vinylpyrrolidone and methacrylamidopropyl trimethylammonium, 2-Pyrrolidinone, 1-ethenyl-, polymer with N,N,N-trimethyl- (+3 more)
INCI: POLYQUATERNIUM-28
Polyquaternium-28 (CAS 131954-48-8) is a cosmetic cosmetic ingredient functioning as Antistatic, Film Forming, Hair Fixative, Conditioning. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 131954-48-8 →
Auto-generated CPSR Part A draft with source citations
Function
Antistatic, Film Forming, Hair Fixative, Conditioning
Safety Rating
EXCELLENT
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
CIR 2012: polymeric trimonium ingredients (including PQ-28) safe as used.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Polyquaternium-28.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
3 property records from structured ingredient metadata.
hair_care
{"hair_function": "styling", "hair_type_suitability": "fine/medium", "curl_pattern_suitability": "all", "porosity_suitability": "all", "protein_sensitivity": "neutral", "moisture_protein_balance": "yes", "cg_method_approved": "not-a-silicone", "silicone_type": "not-a-sulfate", "sulfate_type": "no", "drying_alcohol": "no", "fatty_alcohol": "no", "heat_protectant": "yes", "color_safe": "neutral", "k…
hair_conditioning
{"cas_number": "131954-48-8", "ingredient_class": "cationic_conditioner", "chemical_type": "polyquaternium", "charge_density_meq_g": "1.8", "substantivity_to_hair": "excellent", "deposition_from_shampoo": "yes", "deposition_from_conditioner": "yes", "conditioning_mechanism": "electrostatic", "hair_penetration": "cuticle", "molecular_weight_effect_on_penetration": "copolymer", "wet_combing_force_re…
polymer
{"cas_number": "131954-48-8", "ingredient_class": "film_former/conditioning", "polymer_type": "synthetic_copolymer", "chemical_backbone": "vinyl", "molecular_weight_Da_range": "200000-1800000", "ionic_character": "cationic", "charge_density_meq_g": "2.0-3.8", "pH_viscosity_sensitivity": "moderate", "salt_tolerance": "moderate", "electrolyte_effect_on_viscosity": "moderate", "temperature_viscosity_…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Anti-static agent
Film former
Fixing agent (mordant)
Hair fixative
Expert Verdict
Expert safety assessment and concern-level summary for Polyquaternium-28.
Known Synonyms
2-Methyl-N-[3-(trimethylazaniumyl)propyl]prop-2-enimidate--1-ethenylpyrrolidin-2-one--hydrogen chloride (1/1/1)
Gafquat HS-100
N,N,N-Trimethyl-3-((2-methyl-1-oxo-2-propenyl)amino)-1-propanaminium chloride
Copolymer of vinylpyrrolidone and methacrylamidopropyl trimethylammonium
2-Pyrrolidinone, 1-ethenyl-, polymer with N,N,N-trimethyl-
1-Propanaminium, N,N,N-trimethyl-3-[(2-methyl-1-oxo-2-propen-1-yl)amino]-, chloride (1:1), polymer with 1-ethenyl-2-pyrrolidinone
2-Pyrrolidinone, 1-ethenyl-, polymer with N,N,N-trimethyl-3-[(2-methyl-1-oxo-2-propenyl)amino]-1-propanaminium chloride
UNII-6M8B654MEQ
Chemical Function
Film former
Anti-static agent
Hair fixative
Fixing agent (mordant)
Regulatory Lists
Canada; Personal care; Substances in PCP - Canada (4/2014)
Australian Status
AICIS status: listed_with_terms
Specific information requirements: Obligations to provide information apply. You must tell us within 28 days if the circumstances of your importation or manufacture (introduction) are different to those in our assessment.
Frequently Asked Questions
Is Polyquaternium-28 allowed in the EU?
Polyquaternium-28 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Polyquaternium-28 do in cosmetics?
Polyquaternium-28 functions as: Antistatic, Film Forming, Hair Fixative, Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 131954-48-8.
Compliance Tools
Check Polyquaternium-28 compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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Not Reported
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