Good Cosmetic Ingredient GHS Classified

Distearyldimonium Chloride

INCI: DISTEARYLDIMONIUM CHLORIDE

Distearyldimonium Chloride (CAS 107-64-2) is a cosmetic cosmetic ingredient functioning as Antistatic, Emulsifying, Hair Conditioning, Surfactant. EU Regulation 1223/2009 status: permitted.

CAS Number
107-64-2
Function
Antistatic, Emulsifying, Hair Conditioning, Surfactant
Safety Rating
GOOD

Chemistry & Identifiers

Formula
C38H80ClN
MW
586.5 g/mol
PubChem CID
7879
IUPAC Name
dimethyl(dioctadecyl)azanium chloride
InChIKey
REZZEXDLIUJMMS-UHFFFAOYSA-M
UNII: OM9573ZX3X Wikidata: Q5277336

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes No standalone CIR report. CIR 1982 assessed Quaternium-18 (closely related) as safe.

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Distearyldimonium Chloride - available to Pro subscribers.

Calculate MoS for your specific formulation with the MoS Calculator.

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Short-term Exposure Effects
The substance is corrosive to the eyes. The substance is irritating to the skin.

EU CLP Annex VI Harmonized Classification

Legally binding harmonized classification per Regulation (EC) No 1272/2008 (CLP) Annex VI.

Signal Word
Danger
Pictograms
CorrosiveEnvironmental Hazard
Hazard Class and Category
Eye Dam. 1; Aquatic Acute 1; Aquatic Chronic 1
Hazard Statements
  • H318 Causes serious eye damage
  • H400 Very toxic to aquatic life
  • H410 Very toxic to aquatic life with long lasting effects

Inserted via ATP: CLP00

Additional Ingredient Properties

5 property records from structured ingredient metadata.

ecotoxicity
{"biodegradable": "partial", "biodegradation_days": "120-240", "bioaccumulative": "yes", "aquatic_toxicity_level": "high", "coral_reef_safe": "no", "marine_toxicity": "toxic to aquatic organisms", "freshwater_toxicity": "bioaccumulative", "endocrine_disruptor": "no", "persistent_organic_pollutant": "yes", "microplastic": "no", "nano_particle": "no", "hawaii_banned": "no", "eu_restricted_environmen…
hair_care
{"hair_function": "conditioning", "hair_type_suitability": "coarse", "curl_pattern_suitability": "curly/coily", "porosity_suitability": "low", "protein_sensitivity": "neutral", "moisture_protein_balance": "yes", "cg_method_approved": "not-a-silicone", "silicone_type": "not-a-sulfate", "sulfate_type": "no", "drying_alcohol": "no", "fatty_alcohol": "no", "heat_protectant": "yes", "color_safe": "neut…
hair_conditioning
{"cas_number": "107-64-2", "ingredient_class": "cationic_conditioner", "chemical_type": "quaternary_ammonium", "charge_density_meq_g": "high", "substantivity_to_hair": "excellent", "deposition_from_shampoo": "no", "deposition_from_conditioner": "yes", "conditioning_mechanism": "electrostatic_film_forming", "hair_penetration": "cuticle", "molecular_weight_effect_on_penetration": "long_chain", "wet_…
sensory
{"silky": "waxy", "smooth, glides easily": "smooth, conditioning", "dry-touch, non-greasy": "soft, detangled", "instant": "moderate", "low": "medium", "w/o": "o/w", "very-high": "moderate", "no": "no", "yes": "no", "1.40": "1.45", "transparent": "opaque", "colorless": "white", "excellent": "fair", "light": "medium", "synthetic": "synthetic"}
solubility_hlb
{"water_soluble": "no", "oil_soluble": "yes", "hlb_value": "6.0", "soluble_in": "oils, ethanol", "insoluble_in": "water, glycerin", "log_p": "3.6", "melting_point_c": "65-75", "appearance": "white flakes", "source": "Clariant"}

PubChem Annotations

Safety and regulatory annotations from PubChem (NCBI) aggregated sources.

Safety (2)
Endocrine Disruptors
Potential endocrine disrupting compound
Source: NORMAN Suspect List Exchange
ICSC Safety Card
1296
Source: ILO-WHO International Chemical Safety Cards (ICSCs)

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Anti-static agent Dispersing agent Flow promoter Softener and conditioner Surfactant (surface active agent) Thickening agent

Expert Verdict

Expert safety assessment and concern-level summary for Distearyldimonium Chloride - available to Pro subscribers.

Frequently Asked Questions

Is Distearyldimonium Chloride safe in cosmetics?

Well-established cationic emulsifier with no EU or FDA restrictions; safety inferred from class data on C16-C18 quaternary ammonium salts with oral LD50 greater than 10 g/kg. The EU classifies Distearyldimonium Chloride as "permitted". Safety rating: GOOD.

Is Distearyldimonium Chloride allowed in the EU?

Distearyldimonium Chloride EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Distearyldimonium Chloride do in cosmetics?

Distearyldimonium Chloride functions as: Antistatic, Emulsifying, Hair Conditioning, Surfactant. It is classified as a cosmetic ingredient in our database. CAS number: 107-64-2.

What is the Margin of Safety for Distearyldimonium Chloride?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Distearyldimonium Chloride compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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