Excellent Cosmetic Ingredient

Hydroxypropyl Guar Hydroxypropyltrimonium Chloride

INCI: HYDROXYPROPYL GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE

Hydroxypropyl Guar Hydroxypropyltrimonium Chloride (CAS 71329-50-5) is a cosmetic cosmetic ingredient functioning as Antistatic, Hair Conditioning, Film Forming, Humectant. EU Regulation 1223/2009 status: permitted.

CAS Number
71329-50-5
Function
Antistatic, Hair Conditioning, Film Forming, Humectant
Safety Rating
EXCELLENT

Chemistry & Identifiers

UNII: MVW5LK6LFT

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes CIR concluded safe (2014/2015). Parent guar gum GRAS (21 CFR 184.1339).

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Hydroxypropyl Guar Hydroxypropyltrimonium Chloride - available to Pro subscribers.

Calculate MoS for your specific formulation with the MoS Calculator.

Additional Ingredient Properties

5 property records from structured ingredient metadata.

hair_care
{"hair_function": "conditioning", "hair_type_suitability": "all", "curl_pattern_suitability": "all", "porosity_suitability": "all", "protein_sensitivity": "neutral", "moisture_protein_balance": "yes", "cg_method_approved": "not-a-silicone", "silicone_type": "not-a-sulfate", "sulfate_type": "no", "drying_alcohol": "no", "fatty_alcohol": "no", "heat_protectant": "yes", "color_safe": "neutral", "kera…
hair_conditioning
{"cas_number": "39421-75-5", "ingredient_class": "cationic_conditioner", "chemical_type": "cationic_guar", "charge_density_meq_g": "0.7", "substantivity_to_hair": "excellent", "deposition_from_shampoo": "yes", "deposition_from_conditioner": "yes", "conditioning_mechanism": "electrostatic", "hair_penetration": "cuticle", "molecular_weight_effect_on_penetration": "modified_guar", "wet_combing_force_…
polymer
{"ingredient_class": "thickener/film_former/hair_fixative", "polymer_type": "modified_natural", "chemical_backbone": "other", "molecular_weight_Da_range": "250000-700000", "molecular_weight_distribution_PDI": "2.5-4.5", "crystallinity_pct": "0", "branching_degree": "moderate", "ionic_character": "cationic", "charge_density_meq_g": "0.8-1.8", "viscosity_1pct_aqueous_mPas": "1000-5000", "viscosity_p…
rheology
{"cas_number": "65497-29-2", "rheology_modifier_type": "Natural Polysaccharide - Cationic Guar", "thickening_mechanism": "Chain entanglement and hydrogen bonding", "viscosity_increase_factor": "5000-25000x", "brookfield_viscosity_typical_cps": "5500-16000", "shear_thinning_behavior": "Excellent", "thixotropic": "Yes", "yield_stress_pa": "15-40", "flow_curve_type": "Highly pseudoplastic with yield …
surfactant
{"cas_number": "39421-75-5", "surfactant_type": "cationic", "chemical_class": "amine_oxide", "charge_at_use_ph": "positive", "cmc_critical_micelle_concentration_mm": "0.045965416639339444", "foam_volume_ml_ross_miles": "61", "foam_quality": "minimal", "foam_stability_5min_pct": "52", "cleansing_power_rating_1_to_10": "3.6001085504461554", "oil_emulsification_capacity": "poor", "sebum_removal_effic…

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Anti-static agent Softener and conditioner
Regulatory List Membership (1)
EU Restricted for Children (Cosmetics)

Expert Verdict

Expert safety assessment and concern-level summary for Hydroxypropyl Guar Hydroxypropyltrimonium Chloride - available to Pro subscribers.

Regulatory Flags

eu_children_restricted

Frequently Asked Questions

Is Hydroxypropyl Guar Hydroxypropyltrimonium Chloride safe in cosmetics?

High MW galactomannan derivative with excellent safety profile. CIR concluded safe at 0.04-0.9%. Molecular size prevents skin penetration. Oral LD50 = 12.0 g/kg. The EU classifies Hydroxypropyl Guar Hydroxypropyltrimonium Chloride as "permitted". Safety rating: EXCELLENT.

Is Hydroxypropyl Guar Hydroxypropyltrimonium Chloride allowed in the EU?

Hydroxypropyl Guar Hydroxypropyltrimonium Chloride EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydroxypropyl Guar Hydroxypropyltrimonium Chloride do in cosmetics?

Hydroxypropyl Guar Hydroxypropyltrimonium Chloride functions as: Antistatic, Hair Conditioning, Film Forming, Humectant. It is classified as a cosmetic ingredient in our database. CAS number: 71329-50-5.

What is the Margin of Safety for Hydroxypropyl Guar Hydroxypropyltrimonium Chloride?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Hydroxypropyl Guar Hydroxypropyltrimonium Chloride compliance across multiple jurisdictions:

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Ingredient Decoder
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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