Is Polymethylsilsesquioxane safe in cosmetics?
Polymethylsilsesquioxane has a safety rating of "GOOD" in our database. EU status: restricted. US status: permitted.
Good
Cosmetic Ingredient
Polymethylsilsesquioxane
Also known as: Me silsesquioxanes, MSP-S, MSP-M, PLOS-M, Methyl silsesquioxanes (+4 more)
INCI: POLYMETHYLSILSESQUIOXANE
Polymethylsilsesquioxane (CAS 68554-70-1) is a cosmetic cosmetic ingredient functioning as Viscosity controlling agent, film former. EU Regulation 1223/2009 status: restricted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 68554-70-1 →
Auto-generated CPSR Part A draft with source citations
Function
Viscosity controlling agent, film former
Safety Rating
GOOD
Regulatory Status
EU EU Status
restricted
US US Status
permitted
US Notes
CIR: S - JACT 14(5):373-385, 1995
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Polymethylsilsesquioxane.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
2 property records from structured ingredient metadata.
sensory
{"silky": "powdery", "smooth, glides easily": "silky, velvety", "dry-touch, non-greasy": "dry, smooth", "instant": "instant", "low": "low", "w/o": "w/o", "very-high": "excellent", "no": "yes", "yes": "no", "light-diffusing": "blurring", "1.40": "1.50", "transparent": "opaque", "colorless": "white", "excellent": "excellent", "light": "light", "synthetic": "synthetic"}
silicone
{"cas_number": "68554-54-1", "silicone_class": "silsesquioxane", "molecular_weight_Da": "1800.0", "viscosity_cSt": "powder", "volatility": "non_volatile", "evaporation_rate_relative_to_D5": "0.0001", "refractive_index": "1.415", "specific_gravity": "1.3", "flash_point_C": "200.0", "surface_tension_mN_m": "24.0", "spreading_coefficient": "2.5", "film_forming_ability": "excellent", "skin_feel": "pow…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Opacifer
Regulatory List Membership (1)
FDA Indirect Food Contact Additives
Expert Verdict
Expert safety assessment and concern-level summary for Polymethylsilsesquioxane.
Regulatory Flags
EU Restricted
Known Synonyms
Me silsesquioxanes
MSP-S
MSP-M
PLOS-M
Methyl silsesquioxanes
Tospearl 130
XC 99A3849
Methylsilsesquioxane
Dowsil CF 2403
Chemical Function
Opacifer
Regulatory Lists
CEDI
Indirect additives food contact (10/2018)
inert_ingredient; non_food_use; Pesticides
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Polymethylsilsesquioxane allowed in the EU?
Polymethylsilsesquioxane EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Polymethylsilsesquioxane do in cosmetics?
Polymethylsilsesquioxane functions as: Viscosity controlling agent, film former. It is classified as a cosmetic ingredient in our database. CAS number: 68554-70-1.
Compliance Tools
Check Polymethylsilsesquioxane compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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