Is OXACYCLOHEXADECENONE safe in cosmetics?
OXACYCLOHEXADECENONE has a safety rating of "GOOD" in our database. EU status: permitted.
Good
Cosmetic Ingredient
OXACYCLOHEXADECENONE
Also known as: Globalide, A mixture of: (E)-oxacyclohexadec-12-en-2-one, (E)-oxacyclohexadec-13-en-2-one, (Z)-oxacyclohexadec-(12)-en-2-one, and (Z)-oxacyclohexadec-(13)-en-2-one, A mixture of: (E)-oxacyclohexadec-12-en-2-one; (E)-oxacyclohexadec-13-en-2-one; (Z)-oxacyclohexadec-(12)-en-2-one and (Z)-oxacyclohexadec-(13)-en-2-one, A mixture of: (E)-oxacyclohexadec-12-en-2-one; (E)-oxacyclohexadec-13-en-2-one; a) (Z)-oxacyclohexadec-(12)-en-2-one and b) (Z)-oxacyclohexadec-(13)-en-2-one, Habanolide (+4 more)
OXACYCLOHEXADECENONE (CAS 34902-57-3) is a cosmetic cosmetic ingredient functioning as Fragrance, Perfuming. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 34902-57-3 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance, Perfuming
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
(3E)-1-oxacyclohexadec-3-en-2-one
InChIKey
KHLFMZDGADSQGR-ACCUITESSA-N
Regulatory Status
EU EU Status
permitted
US US Status
Not specifically regulated
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
HRIPT Human Patch Test Studies
2 human repeat insult patch tests aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HRIPT | 111 | 0 | 7559 | 7559 | non-sensitizer |
| HRIPT | - | 0 | 8250 | - | - |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Deodorizer
Fragrance
Regulatory List Membership (1)
IFRA Fragrance Transparency List
Expert Verdict
Expert safety assessment and concern-level summary for OXACYCLOHEXADECENONE.
Regulatory Flags
cosing-sourced
eu-permitted
fragrance
needs-enrichment
ifra_fragrance
Known Synonyms
Globalide
A mixture of: (E)-oxacyclohexadec-12-en-2-one, (E)-oxacyclohexadec-13-en-2-one, (Z)-oxacyclohexadec-(12)-en-2-one, and (Z)-oxacyclohexadec-(13)-en-2-one
A mixture of: (E)-oxacyclohexadec-12-en-2-one; (E)-oxacyclohexadec-13-en-2-one; (Z)-oxacyclohexadec-(12)-en-2-one and (Z)-oxacyclohexadec-(13)-en-2-one
A mixture of: (E)-oxacyclohexadec-12-en-2-one; (E)-oxacyclohexadec-13-en-2-one; a) (Z)-oxacyclohexadec-(12)-en-2-one and b) (Z)-oxacyclohexadec-(13)-en-2-one
Habanolide
Reaction mass of: (E)-oxacyclohexadec-12-en-2-one, (E)-oxacyclohexadec-13-en-2-one, (Z)-oxacyclohexadec-(12)-en-2-one and (Z)-oxacyclohexadec-(13)-en-2-one
reaction mass of: (E)-oxacyclohexadec-12-en-2-one
(E)-oxacyclohexadec-13-en-2-one
a) (Z)-oxacyclohexadec-(12)-en-2-one and b) (Z)-oxacyclohexadec-(13)-en-2-one
Chemical Function
Deodorizer
Fragrance
Regulatory Lists
inert_ingredient; non_food_use; Pesticides
IFRA Transparency
Australian Status
AICIS status: listed_with_terms
Specific information requirements: Obligations to provide information apply. You must tell us within 28 days if the circumstances of your importation or manufacture (introduction) are different to those in our assessment.
Frequently Asked Questions
Is OXACYCLOHEXADECENONE allowed in the EU?
OXACYCLOHEXADECENONE EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does OXACYCLOHEXADECENONE do in cosmetics?
OXACYCLOHEXADECENONE functions as: Fragrance, Perfuming. It is classified as a cosmetic ingredient in our database. CAS number: 34902-57-3.
Is OXACYCLOHEXADECENONE used outside cosmetics?
OXACYCLOHEXADECENONE also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check OXACYCLOHEXADECENONE compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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OXACYCLOHEPTADEC-10-EN-2-ONE
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Browse nearby
Perfuming
OXALIC ACID
Moderate
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Chelating
OXALIDE
Good
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Perfuming
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