NOAEL Data Cosmetic Ingredient

Oxacyclohexadecen-2-one

Also known as: Globalide, A mixture of: (E)-oxacyclohexadec-12-en-2-one, (E)-oxacyclohexadec-13-en-2-one, (Z)-oxacyclohexadec-(12)-en-2-one, and (Z)-oxacyclohexadec-(13)-en-2-one, A mixture of: (E)-oxacyclohexadec-12-en-2-one; (E)-oxacyclohexadec-13-en-2-one; (Z)-oxacyclohexadec-(12)-en-2-one and (Z)-oxacyclohexadec-(13)-en-2-one, A mixture of: (E)-oxacyclohexadec-12-en-2-one; (E)-oxacyclohexadec-13-en-2-one; a) (Z)-oxacyclohexadec-(12)-en-2-one and b) (Z)-oxacyclohexadec-(13)-en-2-one, Habanolide (+4 more)

CAS 34902-57-3

Oxacyclohexadecen-2-one (CAS 34902-57-3) is a chemical substance. Key regulatory status: 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.

View cosmetic safety profile for OXACYCLOHEXADECENONE →

SOURCE noael studies public
NOAEL studies
7
SOURCE chemical inventory jurisdictions
Regulatory lists
2
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 12 fields
Name
Oxacyclohexadecen-2-one
CAS Number
34902-57-3
DTXSID
DTXSID4051374
Synonyms
GlobalideA mixture of: (E)-oxacyclohexadec-12-en-2-one, (E)-oxacyclohexadec-13-en-2-one, (Z)-oxacyclohexadec-(12)-en-2-one, and (Z)-oxacyclohexadec-(13)-en-2-oneA mixture of: (E)-oxacyclohexadec-12-en-2-one; (E)-oxacyclohexadec-13-en-2-one; (Z)-oxacyclohexadec-(12)-en-2-one and (Z)-oxacyclohexadec-(13)-en-2-oneA mixture of: (E)-oxacyclohexadec-12-en-2-one; (E)-oxacyclohexadec-13-en-2-one; a) (Z)-oxacyclohexadec-(12)-en-2-one and b) (Z)-oxacyclohexadec-(13)-en-2-oneHabanolideReaction mass of: (E)-oxacyclohexadec-12-en-2-one, (E)-oxacyclohexadec-13-en-2-one, (Z)-oxacyclohexadec-(12)-en-2-one and (Z)-oxacyclohexadec-(13)-en-2-onereaction mass of: (E)-oxacyclohexadec-12-en-2-one(E)-oxacyclohexadec-13-en-2-onea) (Z)-oxacyclohexadec-(12)-en-2-one and b) (Z)-oxacyclohexadec-(13)-en-2-one

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 9 records
DeodorizerFragrance

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 2 records
ListKeywordSource
inert_ingredient; non_food_use; PesticidesEPACPCat
IFRA TransparencyIFRAIFRA

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 7 of 7 studies
ValueUnitEndpointRouteSpeciesSource
GKS0KPO33VUNIIFDA UNII substance identifier--openFDA substances
GKS0KPO33VUNIIFDA UNII substance identifier--openFDA substances
GKS0KPO33VUNIIFDA UNII substance identifier--openFDA substances
GKS0KPO33VUNIIFDA UNII substance identifier--openFDA substances
-%Incidence of positive responsesDermalHumanNTP_ICE_skin_sensitization
8250ug/cm2Induction dose per skin areaDermalHumanNTP_ICE_skin_sensitization
3unitlessRelative reliability scoreDermalHumanNTP_ICE_skin_sensitization

Showing 7 of 7 studies

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed_with_terms
Conditions
Specific information requirements: Obligations to provide information apply. You must tell us within 28 days if the circumstances of your importation or manufacture (introduction) are different to those in our assessment.

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
View full cosmetic safety profile →

Frequently Asked Questions

What is the NOAEL for Oxacyclohexadecen-2-one?

Oxacyclohexadecen-2-one has 7 NOAEL studies in the database. The lowest reported value is GKS0KPO33V UNII. Source: openFDA substances.

What regulatory lists include Oxacyclohexadecen-2-one?

Oxacyclohexadecen-2-one appears on 2 regulatory/inventory lists including inert_ingredient; non_food_use; Pesticides, IFRA Transparency. Source: EPA CPDat.

Is Oxacyclohexadecen-2-one used in cosmetics?

Yes, Oxacyclohexadecen-2-one is also indexed as a cosmetic ingredient under the name OXACYCLOHEXADECENONE. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Oxacyclohexadecen-2-one come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Is Oxacyclohexadecen-2-one used outside industrial chemicals?

Oxacyclohexadecen-2-one also appears in cosmetics databases.