Is OCTYL ISOBUTYRATE safe in cosmetics?
OCTYL ISOBUTYRATE has a safety rating of "GOOD" in our database. EU status: permitted. US status: allowed.
Good
Cosmetic Ingredient
OCTYL ISOBUTYRATE
Also known as: Acetyl 2-methylpropanoate, Caprylyl isobutyrate, EINECS 203-651-0, FEMA No. 2808, Isobutyric acid, octyl ester (+4 more)
OCTYL ISOBUTYRATE (CAS 109-15-9) is a cosmetic cosmetic ingredient functioning as Perfuming. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 109-15-9 →
Auto-generated CPSR Part A draft with source citations
Chemistry & Identifiers
IUPAC Name
octyl 2-methylpropanoate
InChIKey
PQCYCHFQWMNQRJ-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
allowed
US Notes
Allowed — no specific prohibitions; RIFM safety assessment completed and published (2022)
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 1296 | - | - |
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (2)
JECFA Number
192
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
OCTYL ISOBUTYRATE | 1997 | No safety concern at current levels of intake when used as a flavouring agent | TRS 884-JECFA 49/52 | FAS 40-JECFA 49/267
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (3)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for OCTYL ISOBUTYRATE.
Regulatory Flags
cosing-sourced
eu-permitted
fragrance
needs-enrichment
ifra_fragrance
fda_food_additive
jecfa_safe
Known Synonyms
Acetyl 2-methylpropanoate
Caprylyl isobutyrate
EINECS 203-651-0
FEMA No. 2808
Isobutyric acid, octyl ester
NSC 72024
n-Octyl isobutyrate
Octyl 2-methylpropanoate
UNII-T5819VWJ3T
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
IFRA Transparency
Europe
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
consumer_product
Australian Status
AICIS status: listed
Frequently Asked Questions
Is OCTYL ISOBUTYRATE allowed in the EU?
OCTYL ISOBUTYRATE EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does OCTYL ISOBUTYRATE do in cosmetics?
OCTYL ISOBUTYRATE functions as: Perfuming. It is classified as a cosmetic ingredient in our database. CAS number: 109-15-9.
Is OCTYL ISOBUTYRATE used outside cosmetics?
OCTYL ISOBUTYRATE also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check OCTYL ISOBUTYRATE compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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