Is MENTHONE safe in cosmetics?
MENTHONE has a safety rating of "GOOD" in our database. EU status: permitted.
Good
Cosmetic Ingredient
MENTHONE
Also known as: Cyclohexanone, 5-methyl-2-(1-methylethyl)-, (2R,5S)-rel-, (2R,5S)-5-Methyl-2-(propan-2-yl)cyclohexanone, Cyclohexan-1-one, 2-isopropyl-5-methyl-, racemic, EINECS 201-941-1, EINECS 214-049-2 (+5 more)
MENTHONE (CAS 89-80-5) is a cosmetic cosmetic ingredient functioning as Perfuming. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 89-80-5 →
Auto-generated CPSR Part A draft with source citations
Chemistry & Identifiers
IUPAC Name
trans-(2S,5R)-5-methyl-2-propan-2-ylcyclohexan-1-one
InChIKey
NFLGAXVYCFJBMK-BDAKNGLRSA-N
Regulatory Status
EU EU Status
permitted
US US Status
Not specifically regulated
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 5184 | - | - |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Additional Ingredient Properties
1 property record from structured ingredient metadata.
fragrance_ifra
{"cas_number": "10458-14-7", "ifra_amendment_number": "49", "ifra_restriction_type": "Restricted", "ifra_max_use_level_category_1_pct": "0.14", "ifra_max_use_level_category_4_pct": "2.2", "ifra_max_use_level_category_7_pct": "0.32", "ifra_max_use_level_category_11_pct": "0.065", "eu_allergen_declaration_required": "No", "eu_26_allergens_list": "No", "sccs_opinion_available": "Yes", "sensitization_…
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (2)
JECFA Number
429
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
MENTHONE | 1998 | No safety concern at current levels of intake when used as a flavouring agent | TRS 891-JECFA 51/111 | FAS 42-JECFA 51/381
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (3)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for MENTHONE.
Regulatory Flags
cosing-sourced
eu-permitted
fragrance
needs-enrichment
ifra_fragrance
fda_food_additive
jecfa_safe
Known Synonyms
Cyclohexanone, 5-methyl-2-(1-methylethyl)-, (2R,5S)-rel-
(2R,5S)-5-Methyl-2-(propan-2-yl)cyclohexanone
Cyclohexan-1-one, 2-isopropyl-5-methyl-, racemic
EINECS 201-941-1
EINECS 214-049-2
FEMA No. 2667
p-Menthan-3-one racemic
Menthone racemic
5-Methyl-2-(1-methylethyl)cyclohexanone, trans-
UNII-9NH5J4V8FN
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
IFRA Transparency
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
consumer_product
Europe
IFRA Transparency
Australian Status
AICIS status: listed
Frequently Asked Questions
Is MENTHONE allowed in the EU?
MENTHONE EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does MENTHONE do in cosmetics?
MENTHONE functions as: Perfuming. It is classified as a cosmetic ingredient in our database. CAS number: 89-80-5.
Is MENTHONE used outside cosmetics?
MENTHONE also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check MENTHONE compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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