Good Surfactant NOAEL Data

Laureth-23

Also known as: Ethoxylated C12-14 alcohols, Alcohols, C12-14(even numbered), ethoxylated, UNII-302740L8OX, UNII-93RY22U87E, UNII-G4H4YP2VNC (+4 more)

INCI: LAURETH-23

Laureth-23 (CAS 68439-50-9) is a cosmetic surfactant functioning as Surfactant, Emulsifying, Cleansing, Solubilizer. NOAEL 100 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.

View industrial chemical safety profile for CAS 68439-50-9 →

Auto-generated CPSR Part A draft with source citations
Function
Surfactant, Emulsifying, Cleansing, Solubilizer
Safety Rating
GOOD

Chemistry & Identifiers

EC Number
500-213-3

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes CIR safe use ceiling: up to 6%. FDA VCRP: 218 formulations at ≤5%.

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Laureth-23.

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Laureth-23. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL =200 mg/kg bw/day oral Rabbit developmental ToxValDB_ECHA_IUCLID

Pre-Calculated Safety Assessment

Pre-calculated NOAEL → SED → MoS audit trail for Laureth-23 across SCCS product categories, with measured dermal absorption where available.

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Full
Tonnage Band
100,000 - 1,000,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No

Additional Ingredient Properties

4 property records from structured ingredient metadata.

emulsifier
{"cas_number": "9002-92-0", "ingredient_class": "O/W_emulsifier", "chemical_type": "ethoxylated_fatty_alcohol", "HLB_value": "12.2", "HLB_required_for_oil_phase": "10-14", "emulsion_type_primary": "O/W", "droplet_size_typical_um": "0.3-1", "critical_micelle_concentration_pct": "0.001-0.05", "surface_tension_reduction_mN_m": "31", "interfacial_tension_reduction": "35", "foam_formation": "high", "fo…
emulsion_hlb
{"hlb_value": "16.9", "hlb_required_as_emulsifier": "yes", "emulsifier_type": "o_w", "critical_packing_parameter": "0.18-0.28", "phase_inversion_temperature_c": "85-92", "emulsion_stabilization_mechanism": "steric_stabilization", "co_emulsifier_pairs": "none_required", "optimal_oil_phase_pct": "3-10", "optimal_water_phase_pct": "90-97", "electrolyte_tolerance": "low", "pH_emulsion_stability_range"…
solubility_hlb
{"water_soluble": "yes", "oil_soluble": "no", "hlb_value": "16.9", "soluble_in": "water, ethanol, propylene glycol", "insoluble_in": "oils", "log_p": "-0.5", "appearance": "white paste", "source": "Ineos"}
surfactant
{"cas_number": "9002-92-0", "surfactant_type": "nonionic", "chemical_class": "ethoxylate", "charge_at_use_ph": "neutral", "cmc_critical_micelle_concentration_mm": "0.02848228422342703", "hlb_value": "21.5", "foam_volume_ml_ross_miles": "75", "foam_quality": "airy", "foam_stability_5min_pct": "67", "cleansing_power_rating_1_to_10": "5.1448478279800405", "oil_emulsification_capacity": "good", "sebum…

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Cleaning agent Dispersing agent Emulsifier Fragrance Lubricating agent Surfactant (surface active agent) Wetting agent (non-aqueous)
Regulatory List Membership (2)
IFRA Fragrance Transparency List EPA Safer Chemical Ingredients List (SCIL)

Expert Verdict

Expert safety assessment and concern-level summary for Laureth-23.

Regulatory Flags

NEW_REGULATION epa_safer_alternative ifra_fragrance

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to Laureth-23 by CAS number or substance name.

Studies
1
Lowest NOAEL
200 mg/kg bw/day
Highest NOAEL
200 mg/kg bw/day
ToxValDB_ECHA_IUCLID

Known Synonyms

Ethoxylated C12-14 alcohols Alcohols, C12-14(even numbered), ethoxylated UNII-302740L8OX UNII-93RY22U87E UNII-G4H4YP2VNC UNII-M0LJS773XW UNII-R66I1M1LNH Genapol C 050 alcohols, C12C14, ethoxylated

Chemical Function

Surfactant (surface active agent) Dispersing agent Emulsifier Fragrance

Regulatory Lists

Cleaning products and household care - oven - oven cleaner; Europe Cleaning products and household care - oven - oven cleaner; Europe IFRA Transparency SCIL (9/2019) inert_ingredient; non_food_use; Pesticides fracking; water Cleaning products and household care - laundry and fabric treatment - laundry detergent; Europe

Australian Status

AICIS status: listed

Frequently Asked Questions

Is Laureth-23 safe in cosmetics?

Laureth-23 has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted. 1 toxicological study endpoint(s) are available in our database.

Is Laureth-23 allowed in the EU?

Laureth-23 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Laureth-23 do in cosmetics?

Laureth-23 functions as: Surfactant, Emulsifying, Cleansing, Solubilizer. It is classified as a Surfactant in our database. CAS number: 68439-50-9.

What is the NOAEL for Laureth-23?

The NOAEL (No Observed Adverse Effect Level) for Laureth-23 is =200 mg/kg bw/day based on a developmental study via oral route in Rabbit. Source: ToxValDB_ECHA_IUCLID.

Is Laureth-23 used outside cosmetics?

Laureth-23 also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

Does Laureth-23 have different safety status in cosmetics vs industrial chemicals?

Laureth-23 is classified GHS Danger (H302, H318, H319, H400, H410, H412) in the chemicals database but is allowed in EU cosmetics.

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