Is Lactococcus Ferment Lysate safe in cosmetics?
Lactococcus Ferment Lysate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Lactococcus Ferment Lysate
Also known as: Microgard MG 300, Nisitrol, Novasin, Ambicin N, Delvoplus (+7 more)
INCI: LACTOCOCCUS FERMENT LYSATE
Lactococcus Ferment Lysate (CAS 1414-45-5) is a cosmetic cosmetic ingredient functioning as Ferment / Probiotic ingredient. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 1414-45-5 →
Auto-generated CPSR Part A draft with source citations
Function
Ferment / Probiotic ingredient
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
permitted
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Lactococcus Ferment Lysate.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
10 property records from structured ingredient metadata.
acne
{"anti_acne_mechanism": "anti_inflammatory", "comedogenicity_rating_0_to_5": "0", "acne_type_efficacy": "inflammatory", "sebum_reduction_pct_clinical": "0-5", "prescription_required_usa": "No", "otc_drug_monograph_category": "No", "max_otc_concentration_pct": "No limit", "japan_quasi_drug_anti_acne": "No", "korea_functional_cosmetic_acne": "No", "eu_cosmetic_restriction_acne": "No restriction", "c…
anti_aging
{"anti_aging_claim": "barrier-repair, anti-inflammatory", "mechanism_of_action": "Bioactive phytochemicals, antioxidant compounds", "target_skin_layer": "epidermis", "collagen_stimulation": "No", "elastin_protection": "No", "wrinkle_reduction_pct": "6-12", "clinical_study_duration_weeks": "8", "sample_size": "25", "double_blind": "Yes", "placebo_controlled": "Yes", "published_journal": "Phytothera…
anti_pollution
{"cas_number": "223749-36-8", "ingredient_class": "other", "primary_mechanism": "microbiome_protection", "pollution_types_targeted": "PM2_5", "IR_A_protection": "no", "visible_light_protection": "no", "digital_screen_protection_claim": "no", "PAH_neutralization": "no", "ozone_protection": "no", "mitochondrial_protection": "no", "Nrf2_activation": "no", "AhR_pathway_modulation": "no", "NF_kB_inhibi…
baby_pediatric
{"cas_number": "CAS-FUNC-44", "ingredient_class": "other", "pediatric_safety_rating": "good", "minimum_age_months": "3", "neonatal_safe": "no", "premature_infant_safe": "insufficient_data", "skin_barrier_maturity_consideration": "Probiotic/postbiotic - emerging baby care", "transepidermal_absorption_risk_pediatric": "low", "systemic_exposure_concern_pediatric": "low", "dose_per_kg_body_weight_conc…
deodorant
{"cas_number": "223747-83-5", "ingredient_class": "postbiotic_deodorant", "mechanism_of_action": "microbiome_modulation", "antiperspirant_efficacy_sweat_reduction_pct": "0", "deodorant_efficacy_hours": "12-24", "odor_reduction_pct": "45-65", "bacteriostatic": "no", "bactericidal": "no", "target_bacteria": "promotes beneficial", "microbiome_impact": "prebiotic", "axillary_microbiome_effect": "varie…
depigmentation
{"cas_number": "formulation", "ingredient_class": "keratinocyte_turnover_enhancer", "primary_mechanism_of_action": "Fermentation metabolites provide gentle brightening and barrier support", "secondary_mechanisms": "Variable", "molecular_target": "other", "tyrosinase_inhibition_IC50_uM": "varies", "tyrosinase_inhibition_type": "competitive", "melanin_reduction_pct_in_vitro": "25-45", "melanin_reduc…
fermentation
{"cas_number": "proprietary", "ingredient_class": "fermentation_product", "production_organism": "bacteria", "fermentation_type": "aerobic", "substrate_feedstock": "plant extracts, glucose", "bioactive_compounds_produced": "amino acids, peptides, vitamins, polysaccharides", "mechanism_of_action_skin": "multi-functional bioactive delivery", "skin_benefit_primary": "anti_aging", "skin_benefit_second…
microbiome
{"ingredient_class": "probiotic_lysate", "microbial_source_genus": "Lactococcus", "microbial_source_species": "lactis", "fermentation_substrate": "milk", "live_organism_content": "no", "inactivation_method": "heat", "bioactive_components": "peptides/bacteriocins/lactic_acid", "molecular_weight_range_Da": "5000-30000", "pH_of_ingredient": "4.5-5.5", "mechanism_of_action": "AMP_production/competitiv…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Biocide
Expert Verdict
Expert safety assessment and concern-level summary for Lactococcus Ferment Lysate.
Known Synonyms
Microgard MG 300
Nisitrol
Novasin
Ambicin N
Delvoplus
E 234
L-Lysine, L-isoleucyl-(Z)-2,3-didehydro-2-aminobutanoyl-D-cysteinyl-L-isoleucyl-2,3-didehydroalanyl-L-leucyl-L-cysteinyl-threo-3-mercapto-D-2-aminobutanoyl-L-prolylglycyl-L-cysteinyl-L-lysyl-threo-3-mercapto-D-2-aminobutanoylglycyl-L-alanyl-L-leucyl-L-methionylglycyl-L-cysteinyl-L-asparaginyl-L-methionyl-L-lysyl-threo-3-mercapto-D-2-aminobutanoyl-L-alanyl-threo-3-mercapto-D-2-aminobutanoyl-L-cysteinyl-L-histidyl-L-cysteinyl-L-seryl-L-isoleucyl-L-histidyl-L-valyl-2,3-didehydroalanyl-, cyclic (3→7),(8→11),(13→19),(23→26),(25→28)-pentakis(sulfide)
Nisaplin
Nisin A
Nisin(1-34)
nisina
nisine
Chemical Function
Biocide
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Lactococcus Ferment Lysate allowed in the EU?
Lactococcus Ferment Lysate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Lactococcus Ferment Lysate do in cosmetics?
Lactococcus Ferment Lysate functions as: Ferment / Probiotic ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 1414-45-5.
Compliance Tools
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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