Is GENISTEIN METHYL ETHER safe in cosmetics?
GENISTEIN METHYL ETHER has a safety rating of "GOOD" in our database. EU status: permitted.
Good
Cosmetic Ingredient
GENISTEIN METHYL ETHER
Also known as: EINECS 207-744-7, UNII-U13J6U390T, 5,7-Dihydroxy-4'-methoxy-Isoflavone, 5,7-Dihydroxy-4'-methoxy-Isoflavone (8CI), 5,7-dihydroxy-3-(4-methoxyphenyl)-4H-1-benzopyran-4-one (+3 more)
GENISTEIN METHYL ETHER (CAS 491-80-5) is a cosmetic cosmetic ingredient functioning as Humectant, Skin Conditioning, Skin Protecting. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 491-80-5 →
Auto-generated CPSR Part A draft with source citations
Function
Humectant, Skin Conditioning, Skin Protecting
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
5,7-dihydroxy-3-(4-methoxyphenyl)chromen-4-one
InChIKey
WUADCCWRTIWANL-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
Not specifically regulated
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Endocrine Disruptor Evidence (Expanded)
Cross-referenced EDC classifications, mechanism data, and dose-response evidence from EDLists, SIN List, and cosmetic-specific detail sources.
Cosmetic-Specific Mechanism
Category: other
Receptor targets: ERα, ERβ
LOEC: 1 nM
EU status: allowed
agonist (ERβ-selective)
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (2)
Carcinogen Classification
No indication of carcinogenicity to humans (not listed by IARC).
Source: Toxin and Toxin Target Database (T3DB)
Endocrine Disruptors
Potential endocrine disrupting compound
Source: NORMAN Suspect List Exchange
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Humectant
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for GENISTEIN METHYL ETHER.
Regulatory Flags
cosing-sourced
eu-permitted
skin-conditioning
humectant
needs-enrichment
Known Synonyms
EINECS 207-744-7
UNII-U13J6U390T
5,7-Dihydroxy-4'-methoxy-Isoflavone
5,7-Dihydroxy-4'-methoxy-Isoflavone (8CI)
5,7-dihydroxy-3-(4-methoxyphenyl)-4H-1-benzopyran-4-one
5,7-dihydroxy-3-p-methoxyphenyl-4H-chromen-4-one
Biochanine a
pratensol
Chemical Function
Humectant
Softener and conditioner
Regulatory Lists
Canada; pharmaceutical
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
BIOCHANIN
ChEMBL ID
CHEMBL131921
Frequently Asked Questions
Is GENISTEIN METHYL ETHER allowed in the EU?
GENISTEIN METHYL ETHER EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does GENISTEIN METHYL ETHER do in cosmetics?
GENISTEIN METHYL ETHER functions as: Humectant, Skin Conditioning, Skin Protecting. It is classified as a cosmetic ingredient in our database. CAS number: 491-80-5.
Is GENISTEIN METHYL ETHER used outside cosmetics?
GENISTEIN METHYL ETHER also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
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Ingredient Decoder
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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