Is Fructose Bisphosphate safe in cosmetics?
Fructose Bisphosphate has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Fructose Bisphosphate
Also known as: Diphosphofructose, Fosfructose, Esafosfan, EINECS 207-683-6, Fructose-1,6-bisphosphate (+7 more)
INCI: FRUCTOSE BISPHOSPHATE
Fructose Bisphosphate (CAS 488-69-7) is a cosmetic cosmetic ingredient functioning as Skin Conditioning, Cellular Energy Support. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 488-69-7 →
Auto-generated CPSR Part A draft with source citations
Function
Skin Conditioning, Cellular Energy Support
Safety Rating
EXCELLENT
Chemistry & Identifiers
IUPAC Name
[(2R,3S,4S,5S)-3,4-dihydroxy-5-(phosphonooxymethyl)oxolan-2-yl]methyl dihydrogen phosphate
InChIKey
WSMBXSQDFPTODV-JGWLITMVSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
No specific FDA restrictions; used as a skin-conditioning and energy-metabolism support ingredient
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Fructose Bisphosphate.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Fructose Bisphosphate.
Regulatory Flags
energy-metabolism
cellular-support
endogenous
skin-conditioning
Known Synonyms
Diphosphofructose
Fosfructose
Esafosfan
EINECS 207-683-6
Fructose-1,6-bisphosphate
Harden-Young-Ester
D-arabino-2-Hexulose-1,6-bis(dihydrogenphosphat)
UNII-M7522JYX1H
1,6-di-O-phosphono-beta-D-fructofuranose
[(2R,3S,4R,5R)-2,3,4-trihydroxy-5-(phosphonooxymethyl)oxolan-2-yl]methoxyphosphonic acid
[(2R,3S,4R,5R)-2,3,4-trihydroxy-5-(phosphonooxymethyl)tetrahydrofuran-2-yl]methoxyphosphonic acid
beta-D-fructofuranose 1,6-bisphosphate
Regulatory Lists
pharmaceutical
Canada; pharmaceutical
pharmaceutical
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL1235112
Frequently Asked Questions
Is Fructose Bisphosphate allowed in the EU?
Fructose Bisphosphate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Fructose Bisphosphate do in cosmetics?
Fructose Bisphosphate functions as: Skin Conditioning, Cellular Energy Support. It is classified as a cosmetic ingredient in our database. CAS number: 488-69-7.
Is Fructose Bisphosphate used outside cosmetics?
Fructose Bisphosphate also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Fructose Bisphosphate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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Chemical family
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Chemical family
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FULLERENES
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