Is Baicalein safe in cosmetics?
Baicalein has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Baicalein
Also known as: Biacalein, NSC 661431, UNII-49QAH60606, 5,6,7-Trihydroxyflavone, baicalein (OLD)
INCI: BAICALEIN
Baicalein (CAS 491-67-8) is a cosmetic cosmetic ingredient functioning as Antioxidant, skin conditioning (soothing, anti-inflammatory). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 491-67-8 →
Auto-generated CPSR Part A draft with source citations
Function
Antioxidant, skin conditioning (soothing, anti-inflammatory)
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not specifically restricted; recognized flavonoid used in cosmetics. FDA UNII registered
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Baicalein.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Baicalein.
Known Synonyms
Biacalein
NSC 661431
UNII-49QAH60606
5,6,7-Trihydroxyflavone
baicalein (OLD)
Chemical Function
Softener and conditioner
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
BAICALEIN
ChEMBL ID
CHEMBL8260
Max Phase
2
Frequently Asked Questions
Is Baicalein allowed in the EU?
Baicalein EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Baicalein do in cosmetics?
Baicalein functions as: Antioxidant, skin conditioning (soothing, anti-inflammatory). It is classified as a cosmetic ingredient in our database. CAS number: 491-67-8.
Is Baicalein used outside cosmetics?
Baicalein also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
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Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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