Erythrulose

Also known as: L-Erythrulose, 2-​Butanone, 1,​3,​4-​trihydroxy-​, (3S)​-, 2-Butanone, 1,3,4-trihydroxy-, (S)-, L-glycero-Tetrulose, (3S)-1,3,4-Trihydroxybutan-2-one (+1 more)

INCI: ERYTHRULOSE

Erythrulose (CAS 533-50-6) is a cosmetic cosmetic ingredient functioning as Skin Protecting, Tanning. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.

View industrial chemical safety profile for CAS 533-50-6 →

Auto-generated CPSR Part A draft with source citations
Function
Skin Protecting, Tanning
Safety Rating
GOOD

Chemistry & Identifiers

Formula
C4H8O4
MW
120.1 g/mol
EC Number
443-800-9
PubChem CID
5460032
IUPAC Name
(3S)-1,3,4-trihydroxybutan-2-one
InChIKey
UQPHVQVXLPRNCX-VKHMYHEASA-N

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes Not an approved color additive under 21 CFR Parts 73/74/82; FDA enforcement discretion when used as tanning enhancer with DHA; CIR concluded safe as presently used

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Erythrulose.

Calculate MoS for your specific formulation with the MoS Calculator.

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No

Additional Ingredient Properties

2 property records from structured ingredient metadata.

hair_dye
{"cas_number": "533-50-6", "ingredient_class": "other", "chemical_class": "other", "molecular_weight_Da": "120.10", "color_result_on_hair": "Golden-brown (Maillard reaction)", "shade_range": "blonde", "primary_function": "direct_deposit", "requires_developer": "no", "deposit_only": "yes", "permanence": "semi_permanent", "wash_fastness_shampoos": "5-10", "hair_penetration_depth": "surface_only", "s…
self_tanning
{"cas_number": "533-50-6", "ingredient_class": "self_tanner", "tanning_mechanism": "Maillard_reaction", "color_development_onset_hours": "24.0", "full_color_development_hours": "72", "color_duration_days": "7", "color_depth": "light", "undertone": "neutral", "color_uniformity": "excellent", "fade_pattern": "even", "DHA_concentration_if_applicable_pct": "0", "erythrulose_concentration_pct": "1-3", …

Expert Verdict

Expert safety assessment and concern-level summary for Erythrulose.

Regulatory Flags

self-tanning maillard-reaction biotechnology-derived ketose-sugar dha-synergist nicnas-reviewed cir-reviewed us-regulatory-grey-zone

Known Synonyms

L-Erythrulose 2-​Butanone, 1,​3,​4-​trihydroxy-​, (3S)​- 2-Butanone, 1,3,4-trihydroxy-, (S)- L-glycero-Tetrulose (3S)-1,3,4-Trihydroxybutan-2-one EC No.: 610-990-1

Australian Status

AICIS status: listed_with_terms

Specific information requirements: Obligations to provide information apply. You must tell us within 28 days if the circumstances of your importation or manufacture (introduction) are different to those in our assessment.

Frequently Asked Questions

Is Erythrulose safe in cosmetics?

Erythrulose has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.

Is Erythrulose allowed in the EU?

Erythrulose EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Erythrulose do in cosmetics?

Erythrulose functions as: Skin Protecting, Tanning. It is classified as a cosmetic ingredient in our database. CAS number: 533-50-6.

Is Erythrulose used outside cosmetics?

Erythrulose also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

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