Is Dead Sea Salt safe in cosmetics?
Dead Sea Salt has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted. 4 toxicological study endpoint(s) are available in our database.
Dead Sea Salt
Also known as: KCl, [KCl], Potassium chloride (KCl), EC No.: 231-211-8, Caswell No. 686 (+15 more)
INCI: MARIS SAL
Dead Sea Salt (CAS 7447-40-7) is a cosmetic active ingredient functioning as Skin Conditioning, Mechanical Exfoliant, Osmotic Agent, Mineral Supplementation. NOAEL 1820 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 7447-40-7 →
Auto-generated CPSR Part A draft with source citations
Function
Skin Conditioning, Mechanical Exfoliant, Osmotic Agent, Mineral Supplementation (Mg, Ca, K, Br), Anti-inflammatory, Psoriasis Adjuvant Therapy
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted in cosmetics; no specific FDA restriction; used in bath products and scrubs; heavy metal limits apply (Washington State TFCA: Pb ≤1 ppm from 2025); MoCRA 2026 compliance required
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Dead Sea Salt.
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
4 study endpoints found for Dead Sea Salt. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 195 mg/kg bw/day | oral | dog | Short Term Toxicity | COSMOS_DB |
| NOAEL | 235 mg/kg bw/day | oral | mouse | Developmental | COSMOS_DB |
| NOAEL | 310 mg/kg bw/day | oral | rat | Developmental | COSMOS_DB |
| NOAEL | =310 mg/kg bw/day | oral | Rat | developmental | ToxValDB_ECHA_IUCLID |
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Short-term Exposure Effects
The substance is irritating to the eyes and respiratory tract. Ingestion of large amounts could cause effects on the cardiovascular system. This may result in cardiac dysrhythmia.
Routes of Exposure
The substance can be absorbed into the body by ingestion.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for Dead Sea Salt across SCCS product categories, with measured dermal absorption where available.
EPA ToxValDB — Toxicity Values
6 toxicity values from EPA ToxValDB (aggregated from CCTE, HPV, ToxRefDB, IRIS, and other regulatory dossiers).
| Endpoint | Value | Species | Route | Duration | Source |
|---|---|---|---|---|---|
| LEL | =40 mg/kg-day | Human | oral | short-term | EFSA |
| NOAEL | =310 mg/kg-day | Rat | oral | - | ECHA IUCLID |
| NOAEL | =310 mg/kg-day | Rat | oral | - | ECHA IUCLID |
| NOAEL | >141.96 mg/kg-day | Rat | oral | chronic | ECHA IUCLID |
| LD50 | =1500 mg/kg | Mouse | oral | - | ChemIDplus |
| LD50 | =2600 mg/kg | Rat | oral | - | ChemIDplus |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10,000 - 100,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
Additional Jurisdictional Restrictions (1)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| AU | restricted | - | specific uses |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Chemical reaction regulator
Filler
Flavouring and nutrient
Processing aids not otherwise specified
Thickening agent
Viscosity modifier
pH regulating agent
Regulatory List Membership (2)
EPA Safer Chemical Ingredients List (SCIL)
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for Dead Sea Salt.
Regulatory Flags
heavy-metal-testing-required
marine-origin
psoriasis-clinical-evidence
transdermal-mineral-penetration
mechanical-exfoliant
bromine-content-specify
21-mineral-profile
washington-tfca-1ppm-lead-2025
epa_safer_alternative
fda_food_additive
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Dead Sea Salt by CAS number or substance name.
Studies
4
Lowest NOAEL
195 mg/kg bw/day
Highest NOAEL
310 mg/kg bw/day
COSMOS_DB
ToxValDB_ECHA_IUCLID
Known Synonyms
KCl
[KCl]
Potassium chloride (KCl)
EC No.: 231-211-8
Caswell No. 686
Chloride of potash
Dipotassium dichloride
EINECS 231-211-8
EPA Pesticide Chemical Code 013904
Kalcorid
Kaon-Cl TABS
Kay Ciel
KCl-retard Zyma
Klor-Lyte
Natural sylvite
Potassium muriate
K-Predne-dome
Slow-K tablets
Tripotassium trichloride
Kaon Cl
Chemical Function
Viscosity modifier
Filler
Regulatory Lists
inert_ingredient; Pesticides
Europe; supplements
Europe; food_additive; supplements
animal_products
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
SCIL (9/2019)
Canada; pharmaceutical
Canada; pharmaceutical
fracking; water
inert_ingredient; non_food_use; Pesticides
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
POTASSIUM CHLORIDE
ChEMBL ID
CHEMBL1200731
Max Phase
4
Adverse Event Associations
8747
Frequently Asked Questions
Is Dead Sea Salt allowed in the EU?
Dead Sea Salt EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Dead Sea Salt do in cosmetics?
Dead Sea Salt functions as: Skin Conditioning, Mechanical Exfoliant, Osmotic Agent, Mineral Supplementation (Mg, Ca, K, Br), Anti-inflammatory, Psoriasis Adjuvant Therapy. It is classified as a Active Ingredient in our database. CAS number: 7447-40-7.
What is the NOAEL for Dead Sea Salt?
The NOAEL (No Observed Adverse Effect Level) for Dead Sea Salt is 195 mg/kg bw/day based on a Short Term Toxicity study via oral route in dog. A total of 4 study endpoints are available. Source: COSMOS_DB.
Is Dead Sea Salt used outside cosmetics?
Dead Sea Salt also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Dead Sea Salt compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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