NOAEL Data REACH Registered Cosmetic Ingredient

Potassium chloride

Also known as: KCl, [KCl], Potassium chloride (KCl), EC No.: 231-211-8, Caswell No. 686 (+15 more)

CAS 7447-40-7

Potassium chloride (CAS 7447-40-7) is a chemical substance. Key regulatory status: REACH registered, 10 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH, ILO ICSC.

View cosmetic safety profile for Dead Sea Salt →

SOURCE noael studies public
NOAEL studies
18
SOURCE chemical inventory jurisdictions
Regulatory lists
10
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 26 fields
Name
Potassium chloride
CAS Number
7447-40-7
DTXSID
DTXSID5021178
Molecular Formula
ClH.K
InChI Key
WCUXLLCKKVVCTQ-UHFFFAOYSA-M
Monoisotopic Mass
74.940384
Synonyms
KCl[KCl]Potassium chloride (KCl)EC No.: 231-211-8Caswell No. 686Chloride of potashDipotassium dichlorideEINECS 231-211-8EPA Pesticide Chemical Code 013904KalcoridKaon-Cl TABSKay Ciel

ICSC Chemical Safety

International Chemical Safety Card hazard and exposure summary.

SOURCE ILO/WHO International Chemical Safety Cards 1 records
FieldValue
Short-term EffectsThe substance is irritating to the eyes and respiratory tract. Ingestion of large amounts could cause effects on the cardiovascular system. This may result in cardiac dysrhythmia.
Routes of ExposureThe substance can be absorbed into the body by ingestion.

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 26 records
Viscosity modifierFillerThickening agentProcessing aids not otherwise specifiedChemical reaction regulatorFlavouring and nutrientpH regulating agent

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 10 records
ListKeywordSource
inert_ingredient; PesticidesEPACPCat
Europe; supplementsEUCPCat
Europe; food_additive; supplementsEUCPCat
animal_productsUSDAUnited States Department of Agriculture (USDA)
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)FDAUnited States Food and Drug Administration (FDA)
SCIL (9/2019)USEPASafer Chemical Ingredients List
Canada; pharmaceuticalDrugBankDrugBank
Canada; pharmaceuticalDrugBankDrugBank
fracking; waterNY Department of ConservationCPCat
inert_ingredient; non_food_use; PesticidesEPACPCat

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 18 of 18 studies
ValueUnitEndpointRouteSpeciesSource
=1064mg/m3DNEL systemicinhalationHumanToxValDB_GESTIS_DNEL
660YQ98I10UNIIFDA UNII substance identifier--openFDA substances
660YQ98I10UNIIFDA UNII substance identifier--openFDA substances
660YQ98I10UNIIFDA UNII substance identifier--openFDA substances
660YQ98I10UNIIFDA UNII substance identifier--openFDA substances
=40mg/kg bw/dayLELoralHumanToxValDB_EFSA
>141.96mg/kg bw/dayNOAELoralRatToxValDB_ECHA_IUCLID
195mg/kg bw/dayNOAELoraldogCOSMOS_DB
235mg/kg bw/dayNOAELoralmouseCOSMOS_DB
310mg/kg bw/dayNOAELoralratCOSMOS_DB
=310mg/kg bw/dayNOAELoralRatToxValDB_ECHA_IUCLID
1454mg/kg bw/dayNOAELoralratCOSMOS_DB
1500mg/kg bw/dayNOAELoralratCOSMOS_DB
1551mg/kg bw/dayNOAELoralratCOSMOS_DB
1811mg/kg bw/dayNOAELoralcattleCOSMOS_DB
2000mg/kg bw/dayNOAELoralsheepCOSMOS_DB
2229mg/kg bw/dayNOAELoralratCOSMOS_DB
5250mg/kg bw/dayNOAELoralratCOSMOS_DB

Showing 18 of 18 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
RegisteredPotassium chloride231-211-8ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
active
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL POTASSIUM CHLORIDE
ChEMBL Phase
4
Adverse Events
8747
Bioactivity
2
View full pharmaceutical profile →

Food Safety Data

Same-CAS food additive, ADI, and GRAS records where available.

SOURCE EFSA / FDA GRAS 1 records

ADI: NOT LIMITED mg/kg bw

View full food safety profile →

Cannabis Data

Same-CAS cannabis compliance and lab records where available.

SOURCE Cannabis regulatory / lab data efsa substances

1 cannabis record found in efsa substances.

View full cannabis profile →

Frequently Asked Questions

What is the NOAEL for Potassium chloride?

Potassium chloride has 18 NOAEL studies in the database. The lowest reported value is 1064 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.

What regulatory lists include Potassium chloride?

Potassium chloride appears on 9 regulatory/inventory lists including inert_ingredient; Pesticides, Europe; supplements, Europe; food_additive; supplements, and 6 more. Source: EPA CPDat.

Is Potassium chloride used in cosmetics?

Yes, Potassium chloride is also indexed as a cosmetic ingredient under the name Dead Sea Salt. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Potassium chloride come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, ILO/WHO ICSC, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.

Is Potassium chloride used outside industrial chemicals?

Potassium chloride also appears in cosmetics, pharmaceutical, food safety, cannabis databases.