Is cis-Rose Ketone-2 safe in cosmetics?
cis-Rose Ketone-2 has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
cis-Rose Ketone-2
Also known as: cis-1-(2,6,6-trimethyl-2-cyclohexen-1-yl)-2-buten-1-one, cis-2-Buten-1-one, 1-(2,6,6-trimethyl-2-cyclohexen-1-yl)-, EINECS 245-845-8, UNII-K75Q978U9D
INCI: CIS-ROSE KETONE-2
cis-Rose Ketone-2 (CAS 23726-94-5) is a cosmetic cosmetic ingredient functioning as Fragrance ingredient. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 23726-94-5 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance ingredient
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
(Z)-1-(2,6,6-trimethylcyclohex-2-en-1-yl)but-2-en-1-one
InChIKey
CRIGTVCBMUKRSL-ALCCZGGFSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not restricted by FDA; no CIR monograph
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for cis-Rose Ketone-2.
Calculate MoS for your specific formulation with the MoS Calculator.
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
BRIN Brazil/India Cosmetics
Brazil: Restricted · max b) 0,02%
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (1)
IFRA Fragrance Transparency List
Expert Verdict
Expert safety assessment and concern-level summary for cis-Rose Ketone-2.
Regulatory Flags
fragrance-component
ifra_fragrance
Known Synonyms
cis-1-(2,6,6-trimethyl-2-cyclohexen-1-yl)-2-buten-1-one
cis-2-Buten-1-one, 1-(2,6,6-trimethyl-2-cyclohexen-1-yl)-
EINECS 245-845-8
UNII-K75Q978U9D
Chemical Function
Flavouring and nutrient
Fragrance
Regulatory Lists
IFRA Transparency
Europe
Australian Status
AICIS status: listed
Frequently Asked Questions
Is cis-Rose Ketone-2 allowed in the EU?
cis-Rose Ketone-2 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does cis-Rose Ketone-2 do in cosmetics?
cis-Rose Ketone-2 functions as: Fragrance ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 23726-94-5.
Compliance Tools
Check cis-Rose Ketone-2 compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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Chemical family
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trans-Rose Ketone-2
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Chemical family
Fragrance / Perfuming
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