What is the NOAEL for (Z)-1-(2,6,6-Trimethyl-2-cyclohexen-1-yl)-2-buten-1-one?
(Z)-1-(2,6,6-Trimethyl-2-cyclohexen-1-yl)-2-buten-1-one has 4 NOAEL studies in the database. The lowest reported value is K75Q978U9D UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
(Z)-1-(2,6,6-Trimethyl-2-cyclohexen-1-yl)-2-buten-1-one
Also known as: cis-1-(2,6,6-trimethyl-2-cyclohexen-1-yl)-2-buten-1-one, cis-2-Buten-1-one, 1-(2,6,6-trimethyl-2-cyclohexen-1-yl)-, EINECS 245-845-8, UNII-K75Q978U9D
CAS 23726-94-5
(Z)-1-(2,6,6-Trimethyl-2-cyclohexen-1-yl)-2-buten-1-one (CAS 23726-94-5) is a chemical substance. Key regulatory status: 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
10 fields
Name
(Z)-1-(2,6,6-Trimethyl-2-cyclohexen-1-yl)-2-buten-1-one
CAS Number
23726-94-5
DTXSID
DTXSID2051891
Molecular Formula
C13H20O
InChI Key
CRIGTVCBMUKRSL-ALCCZGGFSA-N
Monoisotopic Mass
192.151415
Synonyms
cis-1-(2,6,6-trimethyl-2-cyclohexen-1-yl)-2-buten-1-onecis-2-Buten-1-one, 1-(2,6,6-trimethyl-2-cyclohexen-1-yl)-EINECS 245-845-8UNII-K75Q978U9D
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
2 records
Flavouring and nutrientFragrance
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| Europe | European Commission | Fl@vis |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| K75Q978U9D | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| K75Q978U9D | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| K75Q978U9D | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| K75Q978U9D | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include (Z)-1-(2,6,6-Trimethyl-2-cyclohexen-1-yl)-2-buten-1-one?
(Z)-1-(2,6,6-Trimethyl-2-cyclohexen-1-yl)-2-buten-1-one appears on 2 regulatory/inventory lists including IFRA Transparency, Europe. Source: EPA CPDat.
Is (Z)-1-(2,6,6-Trimethyl-2-cyclohexen-1-yl)-2-buten-1-one used in cosmetics?
Yes, (Z)-1-(2,6,6-Trimethyl-2-cyclohexen-1-yl)-2-buten-1-one is also indexed as a cosmetic ingredient under the name cis-Rose Ketone-2. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for (Z)-1-(2,6,6-Trimethyl-2-cyclohexen-1-yl)-2-buten-1-one come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is (Z)-1-(2,6,6-Trimethyl-2-cyclohexen-1-yl)-2-buten-1-one used outside industrial chemicals?
(Z)-1-(2,6,6-Trimethyl-2-cyclohexen-1-yl)-2-buten-1-one also appears in cosmetics, cannabis databases.