Is Cilostamide safe in cosmetics?
Cilostamide has a safety rating of "POOR" in our database. EU status: permitted. US status: permitted.
Poor
Cosmetic Ingredient
Cilostamide
Also known as: Butanamide, N-cyclohexyl-4-((1,2-dihydro-2-oxo-6-quinolinyl)oxy)-N-methyl-, Cilostamida, Cilostamidum, UNII-45S5605Q18
INCI: CILOSTAMIDE
Cilostamide (CAS 68550-75-4) is a cosmetic cosmetic ingredient functioning as Skin conditioning. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 68550-75-4 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning
Safety Rating
POOR
Chemistry & Identifiers
IUPAC Name
N-cyclohexyl-N-methyl-4-[(2-oxo-1H-quinolin-6-yl)oxy]butanamide
InChIKey
UIAYVIIHMORPSJ-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not specifically regulated for cosmetics; primarily a research biochemical (PDE III inhibitor)
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Cilostamide.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Cilostamide.
Known Synonyms
Butanamide, N-cyclohexyl-4-((1,2-dihydro-2-oxo-6-quinolinyl)oxy)-N-methyl-
Cilostamida
Cilostamidum
UNII-45S5605Q18
Regulatory Lists
pharmaceutical
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
CILOSTAMIDE
ChEMBL ID
CHEMBL34431
Max Phase
2
Frequently Asked Questions
Is Cilostamide allowed in the EU?
Cilostamide EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Cilostamide do in cosmetics?
Cilostamide functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 68550-75-4.
Is Cilostamide used outside cosmetics?
Cilostamide also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Cilostamide compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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