Poor Fragrance Sensitization Data

Chloroatranol

Also known as: Chloroantrol, Benzaldehyde,3-chloro-2,6-dihydroxy-4-methyl-

INCI: CHLOROATRANOL

Chloroatranol (CAS 57074-21-2) is a cosmetic fragrance functioning as Fragrance. EU Regulation 1223/2009 status: prohibited, max 0%. Industrial safety data is also available in the chemical safety database.

View industrial chemical safety profile for CAS 57074-21-2 →

Auto-generated CPSR Part A draft with source citations
Function
Fragrance
Safety Rating
POOR

Chemistry & Identifiers

Regulatory Status

EU EU Status prohibited
EU Max Conc. 0%
US US Status permitted
US Notes No federal ban; voluntarily avoided by major brands; indirect exposure via oakmoss and treemoss extracts

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Chloroatranol.

Calculate MoS for your specific formulation with the MoS Calculator.

Sensitization Profile

Contact sensitization data for Chloroatranol based on clinical patch test studies and IFRA standards.

Sensitization Rate
low
Allergen Class
fragrance
EU Allergen Listed
yes
Patch Test Positive Rate
0.2%
Cross-reactivity Group
none
Reaction Type
contact-dermatitis
IFRA Restricted

Source: EU 2023/1545; SCCS

EU CosIng Annex Listing

European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.

Annex II — Prohibited
Ref: 1382
(EU) 2017/1410

Expanded Jurisdictional Detail

Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.

SA Saudi SFDA (II - Prohibited)
ASEAN Cosmetic Directive (II)
Ref: 1382
BRIN Brazil/India Cosmetics
India: Prohibited (GNRAS)
Additional Jurisdictional Restrictions (2)
Jurisdiction Status Max % Product Type
CN banned - -
KR prohibited - -

Additional Ingredient Properties

2 property records from structured ingredient metadata.

allergen_detail
{"eu_allergen_listed": "yes", "allergen_class": "fragrance", "patch_test_frequency_pct": "0.2", "sensitization_rate": "low", "common_reaction_type": "contact-dermatitis", "ifra_restricted": "yes", "source": "EU 2023/1545; SCCS"}
regulatory
{"eu_status": "banned", "us_status": "allowed", "eu_max_concentration": "0", "restricted_in": "all products", "ban_date": "2019-08-23", "regulation_reference": "Annex II/1406"}

Function Categories & List Membership

Regulatory List Membership (2)
EU Banned in Cosmetics EU CosIng Cosmetics Ingredient Database

Expert Verdict

Expert safety assessment and concern-level summary for Chloroatranol.

Regulatory Flags

eu-banned annex-ii contact-allergen eu-2017-1410 natural-origin oakmoss-constituent eu_banned_cosmetics eu_cosing_listed

Known Synonyms

Chloroantrol Benzaldehyde,3-chloro-2,6-dihydroxy-4-methyl-

Regulatory Lists

banned; Europe; Personal care

Frequently Asked Questions

Is Chloroatranol safe in cosmetics?

Chloroatranol has a safety rating of "POOR" in our database. EU status: prohibited. US status: permitted.

Is Chloroatranol allowed in the EU?

Chloroatranol EU regulatory status: prohibited. Maximum allowed concentration: 0%. This is based on EU Regulation 1223/2009 and its amendments.

What does Chloroatranol do in cosmetics?

Chloroatranol functions as: Fragrance. It is classified as a Fragrance in our database. CAS number: 57074-21-2.

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