Is Beta-Pinenes safe in cosmetics?
Beta-Pinenes has a safety rating of "MODERATE" in our database. EU status: restricted. US status: permitted.
Moderate
Cosmetic Ingredient
Beta-Pinenes
Also known as: Bicyclo[3.1.1]heptane, 6,6-dimethyl-2-methylene-, 2(10)-Pinene, 6,6-Dimethyl-2-methylenebicyclo[3.1.1]heptane, (+/-)-β-Pinene, (+/-)-2(10)-Pinene (+15 more)
INCI: BETA-PINENES
Beta-Pinenes (CAS 127-91-3) is a cosmetic cosmetic ingredient functioning as Fragrance (perfuming). EU Regulation 1223/2009 status: restricted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 127-91-3 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Beta-Pinenes is classified GHS Danger (H226, H304, H315, H317, H331, H335, H400, H410) in the chemicals database but is restricted in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Fragrance (perfuming)
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
6,6-dimethyl-2-methylidenebicyclo[3.1.1]heptane
InChIKey
WTARULDDTDQWMU-UHFFFAOYSA-N
Regulatory Status
EU EU Status
restricted
US US Status
permitted
US Notes
Allowed - not listed on any FDA prohibited or restricted list; classified as GRAS for flavoring and permitted in cosmetics under general safety provisions
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Beta-Pinenes.
Calculate MoS for your specific formulation with the MoS Calculator.
EPA ToxValDB — Toxicity Values
10 toxicity values from EPA ToxValDB (aggregated from CCTE, HPV, ToxRefDB, IRIS, and other regulatory dossiers).
| Endpoint | Value | Species | Route | Duration | Source |
|---|---|---|---|---|---|
| NOAEL | =222 mg/kg-day | Rat | oral | subchronic | EFSA |
| NOAEL | =222 mg/kg-day | Rat | oral | subchronic | EFSA |
| LD50 | =3387 mg/kg | Rat | injection | - | HPVIS |
| LD50 | =3415 mg/kg | Rat | injection | - | HPVIS |
| LD50 | =3388 mg/kg | Rat | injection | - | HPVIS |
| LOAEL | =860 mg/kg-day | Rat | oral | short-term | HPVIS |
| NOAEL | =688 mg/kg-day | Rat | oral | short-term | HPVIS |
| NOAEL | =688 mg/kg-day | Rat | oral | short-term | HPVIS |
| LD50 | >5000 mg/kg | Rabbit | dermal | - | HPVIS |
| LD50 | >5000 mg/kg | Rat | oral | - | HPVIS |
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 8100 | - | - |
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (1)
Skin Eye Respiratory Irritation
Irritating to eyes, respiratory system and skin... /(-)-Beta-pinene/ | ...Irritant to skin and mucous membranes
Source: Hazardous Substances Data Bank (HSDB)
Regulatory (4)
JECFA Number
1330
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
6,6-DIMETHYL-2-METHYLENEBICYCLO[3.1.1]HEPTANE | 2004 | No safety concern at current levels of intake when used as a flavouring agent | TRS 928-JECFA 63/64 | FAS 54-JECFA 63/235
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
beta-PINENE | 2004 | No safety concern at current levels of intake when used as a flavouring agent | TRS 928-JECFA 63/64 | FAS 54-JECFA 63/235
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
PSEUDOPINENE | 2004 | No safety concern at current levels of intake when used as a flavouring agent | TRS 928-JECFA 63/64 | FAS 54-JECFA 63/235
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (3)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for Beta-Pinenes.
Regulatory Flags
potential-allergen
fragrance-component
ifra_fragrance
fda_food_additive
Known Synonyms
Bicyclo[3.1.1]heptane, 6,6-dimethyl-2-methylene-
2(10)-Pinene
6,6-Dimethyl-2-methylenebicyclo[3.1.1]heptane
(+/-)-β-Pinene
(+/-)-2(10)-Pinene
(+/-)-6,6-Dimethyl-2-methylenebicyclo[3.1.1]heptane
Nopinen
Nopinene
Pseudopinen
Pseudopinene
Terebenthene
PC 600 (pesticide)
β-Pinene
6,6-Dimethyl-2-methylenebicyclo(3.1.1)heptane
EINECS 204-872-5
EINECS 245-424-9
FEMA No. 2903
2,2,6-Trimethylbicyclo(3.1.1)hept-2-ene
UNII-4MS8VHZ1HJ
2,2,6-Trimethylbicyclo[3.1.1]hept-2-ene
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
air; detected; emissions; Europe; Vehicle - car interior
air; detected; emissions; Europe; Vehicle - car interior
air; detected; emissions; Europe; Vehicle - car interior
air; emissions; Europe; nondetect; Vehicle - car interior
air; detected; emissions; Europe; Vehicle - car interior
air; detected; emissions; Europe; Vehicle - car interior
air; detected; emissions; Europe; Vehicle - car interior
air; detected; emissions; Europe; Vehicle - car interior
air; detected; emissions; Europe; Vehicle - car interior
air; detected; emissions; Europe; Vehicle - car interior
Cleaning products and household care - laundry and fabric treatment - laundry stain remover; detected; Europe
Cleaning products and household care - laundry and fabric treatment - laundry stain remover; detected; Europe
air; detected; emissions; Europe; Toys and children's products
air; consumer_product; detected; emissions
air; Cleaning products and household care - laundry and fabric treatment; detected; emissions
air; detected; emissions; Personal care
air; Cleaning products and household care; detected; emissions
air; Cleaning products and household care - air freshener; detected; emissions
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Beta-Pinenes allowed in the EU?
Beta-Pinenes EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Beta-Pinenes do in cosmetics?
Beta-Pinenes functions as: Fragrance (perfuming). It is classified as a cosmetic ingredient in our database. CAS number: 127-91-3.
Is Beta-Pinenes used outside cosmetics?
Beta-Pinenes also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Beta-Pinenes have different safety status in cosmetics vs industrial chemicals?
Beta-Pinenes is classified GHS Danger (H226, H304, H315, H317, H331, H335, H400, H410) in the chemicals database but is restricted in EU cosmetics.
Compliance Tools
Check Beta-Pinenes compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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